exRNAdisease

Entry Detail

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General Information

Database ID: exR0352047 RNA Name: hsa-miR-1294 RNA Type: miRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 154347153 End Site(bp): 154347174 External Links: hsa-miR-1294

Disease Information

Disease Name: Polycystic Ovary Syndrome Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D011085 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID: GSE86241 Description: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Experimental Design: Disease vs Control Case Disease Type: Polycystic Ovary Syndrome Case Disease SubType: NA Case Sample: Polycystic Ovary Syndrome Control Sample: Control Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CYB5R3 chr22 42617840 42649392 - STK40 chr1 36339624 36385896 - EIF4A1 chr17 7572706 7579006 + TRAPPC10 chr21 44012309 44106552 + ABCA1 chr9 104781006 104928155 - POGK chr1 166839447 166856344 + FGFR1 chr8 38400215 38468834 - KMT2A chr11 118436490 118526832 + RAB8A chr19 16111889 16134234 + TEX261 chr2 70985942 70994873 - ANKRD49 chr11 94493979 94499578 + PGRMC1 chrX 119236245 119244466 + PTMS chr12 6765516 6770952 + CRY2 chr11 45847118 45883248 + PTP4A1 chr6 63521746 63583436 + APLP2 chr11 130068147 130144811 + CDKN1B chr12 12715058 12722369 + UBE2G2 chr21 44768580 44801826 - PDPR chr16 70113626 70162537 + AKT2 chr19 40230317 40285536 - RNF157 chr17 76142465 76240493 - ZHX3 chr20 41178448 41317672 - ARHGAP28 chr18 6729718 6915716 + PRRC2B chr9 131373636 131500197 + FYCO1 chr3 45917899 45995824 - ZNF512B chr20 63956704 63969930 - SMAD7 chr18 48919853 48952052 - PDE4DIP chr1 148808181 149048286 + TAGLN2 chr1 159918107 159925732 - NACC1 chr19 13116862 13141147 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000247 chr10 74474868 74475660 + hsa_circ_0000798 chr17 65941524 65944422 + hsa_circ_0000246 chr10 74468040 74475660 + hsa_circ_0001085 chr2 191765289 191789319 + hsa_circ_0000744 chr17 15968183 15971435 - hsa_circ_0000799 chr17 65941524 65972074 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007161.3 chr7 7640752 8004053 + AC021078.1 chr5 149494314 149504670 - AC022150.4 chr19 52650437 52653284 - AL022311.1 chr22 37876148 37895563 + H19 chr11 1995176 2001470 - LINC00265 chr7 39733430 39793092 + NEAT1 chr11 65422774 65445540 + TUG1 chr22 30969245 30979395 + Display:

Experiment Detail

GEO ID: GSE86241 Sample Source: Blood Source Fraction: Serum Platform: GPL21575 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1951 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea). RNA library preparation protocol: Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID: 27677182 Title: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Author: Song DK, Sung YA, Lee H Journal: PLoS One. 2016 Sep 27;11(9):e0163756. Description: The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.