Entry Detail



General Information

Database ID:exR0352077
RNA Name:hsa-miR-136-5p
RNA Type:miRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):100884716End Site(bp):100884738
External Links:hsa-miR-136-5p



Disease Information

Disease Name:Polycystic Ovary Syndrome
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D011085
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary



Expression Detail

GEO ID:GSE86241
Description:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:Disease vs Control
Case Disease Type:Polycystic Ovary Syndrome
Case Disease SubType:NA
Case Sample:Polycystic Ovary Syndrome
Control Sample:Control
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACVR1B
chr12
51951699
51997078
+
CREG1
chr1
167529117
167553805
-
PGK1
chrX
77910739
78129295
+
PIK3R1
chr5
68215756
68301821
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001387
chr4
1902352
1936989
+
hsa_circ_0000744
chr17
15968183
15971435
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
DSCAM-AS1
chr21
40383083
40385358
+
GAS5
chr1
173858559
173868882
-
LZTS1-AS1
chr8
20275773
20290458
+
MALAT1
chr11
65497688
65506516
+
MIR4435-2HG
chr2
111006015
111523376
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE86241
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21575
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1951
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.



Reference

PMID:27677182
Title:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:Song DK, Sung YA, Lee H
Journal:PLoS One. 2016 Sep 27;11(9):e0163756.
Description:The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.