exRNAdisease

Entry Detail

General Information

Database ID:

exR0352084

RNA Name:

hsa-miR-144-3p

RNA Type:

miRNA

Chromosome:

chr17

Starnd:

-

Coordinate:

Start Site(bp):

28861548

End Site(bp):

28861567

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ANXA2	chr15	60347134	60402883	-
ARHGAP18	chr6	129576132	129710177	-
CNOT11	chr2	101252886	101270316	+
EPHA7	chr6	93240020	93419559	-
G3BP2	chr4	75642782	75724525	-
GABPB1	chr15	50275392	50355408	-
IKZF2	chr2	212999691	213152427	-
RAB15	chr14	64945814	64973226	-
ROCK2	chr2	11179759	11348330	-
SGPP1	chr14	63684216	63728065	-
USP47	chr11	11841423	11961887	+
ZNF695	chr1	246945547	247008093	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001376	chr3	194169185	194175121	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC010980.2	chr2	222317242	222318653	-
AC022167.2	chr16	8848105	8860456	+
AC093010.3	chr3	114314501	114329714	-
AF254983.1	chr21	10482738	10605716	+
ARHGAP27P1-BPTFP1-KPNA2P3	chr17	64749663	64781707	-
EBLN3P	chr9	37079645	37090928	+
HCG11	chr6	26521709	26527404	+
LINC00662	chr19	27681072	27794005	-
MALAT1	chr11	65497688	65506516	+
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
OTUD6B-AS1	chr8	91059318	91070583	-
SDCBP2-AS1	chr20	1325405	1378735	+
TUG1	chr22	30969245	30979395	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.