exRNAdisease

Entry Detail

General Information

Database ID:

exR0352126

RNA Name:

hsa-miR-183-5p

RNA Type:

miRNA

Chromosome:

chr7

Starnd:

-

Coordinate:

Start Site(bp):

129774967

End Site(bp):

129774988

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
CPNE3	chr8	86514435	86561498	+
ENAH	chr1	225486835	225653142	-
GAPDH	chr12	6534512	6538374	+
GNG5	chr1	84498325	84506581	-
MYLIP	chr6	16129086	16148248	+
NCK2	chr2	105744912	105894274	+
NDST1	chr5	150485818	150558211	+
NR4A2	chr2	156324437	156342348	-
PRKAR2A	chr3	48744597	48847874	-
RAB8A	chr19	16111889	16134234	+
RBFOX2	chr22	35738736	36028824	-
RNF169	chr11	74748849	74842413	+
RTL8A	chrX	135050932	135052196	-
RTL8B	chrX	135020513	135022542	-
SIN3A	chr15	75369379	75455842	-
TGOLN2	chr2	85318020	85328296	-
VANGL1	chr1	115641970	115698224	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001164	chr20	45891031	45923523	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC126365.1	chr17	20788071	20789584	+
AL132780.1	chr14	22929607	22956374	+
KCNQ1OT1	chr11	2608328	2699994	-
MIRLET7BHG	chr22	46053869	46113928	+
NEAT1	chr11	65422774	65445540	+
OIP5-AS1	chr15	41283990	41309737	+
SNHG16	chr17	76557764	76565348	+

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.