exRNAdisease

Entry Detail

General Information

Database ID:

exR0352165

RNA Name:

hsa-miR-198

RNA Type:

miRNA

Chromosome:

chr3

Starnd:

-

Coordinate:

Start Site(bp):

120395703

End Site(bp):

120395724

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
C18orf25	chr18	46173553	46266992	+
CGN	chr1	151510510	151538692	+
CS	chr12	56271699	56300391	-
FSTL1	chr3	120392293	120450993	-
UBE2K	chr4	39698109	39782792	+
CCDC103	chr17	44899142	44905390	+
CLTC	chr17	59619689	59696956	+
FAM187A	chr17	44899712	44905390	+
LRRC20	chr10	70298970	70382650	-
MAP1B	chr5	72107234	72209565	+
NECTIN2	chr19	44846175	44889223	+
RRP7A	chr22	42508344	42519796	-
TPGS2	chr18	36777647	36829216	-
TUBA1A	chr12	49184795	49189080	-
ZNF281	chr1	200404940	200410056	-

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
FTX	chrX	73940435	74293574	-

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.