exRNAdisease

Entry Detail

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General Information

Database ID: exR0352168 RNA Name: hsa-miR-199b-5p RNA Type: miRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 128244783 End Site(bp): 128244805 External Links: hsa-miR-199b-5p

Disease Information

Disease Name: Polycystic Ovary Syndrome Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D011085 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID: GSE86241 Description: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Experimental Design: Disease vs Control Case Disease Type: Polycystic Ovary Syndrome Case Disease SubType: NA Case Sample: Polycystic Ovary Syndrome Control Sample: Control Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDH3B2 chr11 67662160 67681224 - ATP9A chr20 51596514 51768390 - CHD2 chr15 92900189 93027996 + COL4A2 chr13 110305812 110513209 + COX6A1 chr12 120438090 120440737 + FAM222B chr17 28755978 28855232 - FOSL2 chr2 28392448 28417317 + HMGCS1 chr5 43287470 43313512 - KRT80 chr12 52168996 52192014 - MYRF chr11 61752642 61788518 + NFE2L1 chr17 48048329 48061545 + SLC7A5 chr16 87830023 87869507 - WNT5A chr3 55465715 55490539 - XPO6 chr16 28097979 28211920 - ZMIZ1 chr10 79068966 79316528 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000591 chr15 41961025 41962156 + hsa_circ_0001005 chr2 53921020 53978078 - hsa_circ_0000892 chr19 11941431 12014514 + hsa_circ_0000931 chr19 38226804 38231095 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004951.4 chr7 43951910 44019151 - AC095055.1 chr4 151139991 151141103 + BX284668.2 chr1 16870945 16883659 + LINC01783 chr1 16533886 16536172 - POLR2J4 chr7 43940895 44019175 - SNHG12 chr1 28578538 28583132 - TMPO-AS1 chr12 98512973 98516422 - Display:

Experiment Detail

GEO ID: GSE86241 Sample Source: Blood Source Fraction: Serum Platform: GPL21575 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1951 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea). RNA library preparation protocol: Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID: 27677182 Title: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Author: Song DK, Sung YA, Lee H Journal: PLoS One. 2016 Sep 27;11(9):e0163756. Description: The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.