exRNAdisease

Entry Detail

General Information

Database ID:

exR0352181

RNA Name:

hsa-miR-204-5p

RNA Type:

miRNA

Chromosome:

chr9

Starnd:

-

Coordinate:

Start Site(bp):

70810031

End Site(bp):

70810052

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AK2	chr1	33007940	33080996	-
C5orf51	chr5	41904188	41921636	+
CA12	chr15	63321378	63381846	-
CDT1	chr16	88803789	88809258	+
HMOX1	chr22	35380361	35394207	+
MDK	chr11	46380756	46383837	+
MLXIP	chr12	122078756	122147344	+
RCC2	chr1	17406760	17439677	-
RDH11	chr14	67676800	67695793	-
STARD13	chr13	33103137	33350630	-
TMEM237	chr2	201620184	201643570	-
VASP	chr19	45506579	45526983	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001588	chr6	26204839	26205043	+
hsa_circ_0001387	chr4	1902352	1936989	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC010442.1	chr5	466124	473098	-
AP000553.1	chr22	21652270	21670237	+
DSCAM-AS1	chr21	40383083	40385358	+
EBLN3P	chr9	37079645	37090928	+
MALAT1	chr11	65497688	65506516	+
MCM3AP-AS1	chr21	46229196	46259390	+
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.