exRNAdisease

Entry Detail

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General Information

Database ID: exR0352244 RNA Name: hsa-miR-29b-3p RNA Type: miRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 130877467 End Site(bp): 130877489 External Links: hsa-miR-29b-3p

Disease Information

Disease Name: Polycystic Ovary Syndrome Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D011085 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID: GSE86241 Description: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Experimental Design: Disease vs Control Case Disease Type: Polycystic Ovary Syndrome Case Disease SubType: NA Case Sample: Polycystic Ovary Syndrome Control Sample: Control Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AMER1 chrX 64185117 64205708 - APH1A chr1 150265399 150269580 - APP chr21 25880550 26171128 - BACH2 chr6 89926528 90296908 - BIRC5 chr17 78214186 78225636 + C1QTNF6 chr22 37180166 37199385 - CALU chr7 128739292 128773400 + CREG1 chr1 167529117 167553805 - FASN chr17 82078338 82098294 - KLHL28 chr14 44924319 45042322 - KMT5C chr19 55339853 55348121 + MDN1 chr6 89642498 89819794 - NASP chr1 45583846 45618904 + NMI chr2 151270470 151289894 - PER3 chr1 7784320 7845177 + PGK1 chrX 77910739 78129295 + QKI chr6 163414000 163578592 + RNF138 chr18 32091874 32131561 + SH3GLB1 chr1 86704570 86748184 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000018 chr1 15860731 15863309 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007036.3 chr7 30157531 30159534 + AC012146.1 chr17 5111468 5115004 + AC018521.1 chr17 47945424 47981736 + AL137129.1 chr14 61734138 61776260 + AL355488.1 chr1 110370154 110373003 + AL391244.1 chr1 1420245 1422691 + AP001432.1 chr21 37221419 37237744 + H19 chr11 1995176 2001470 - MIR4458HG chr5 8450701 8486930 + MIR497HG chr17 7015818 7019659 - MIRLET7BHG chr22 46053869 46113928 + NEAT1 chr11 65422774 65445540 + OIP5-AS1 chr15 41283990 41309737 + TUG1 chr22 30969245 30979395 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE86241 Sample Source: Blood Source Fraction: Serum Platform: GPL21575 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1951 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea). RNA library preparation protocol: Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID: 27677182 Title: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Author: Song DK, Sung YA, Lee H Journal: PLoS One. 2016 Sep 27;11(9):e0163756. Description: The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.