exRNAdisease

Entry Detail

General Information

Database ID:

exR0352353

RNA Name:

hsa-miR-324-3p

RNA Type:

miRNA

Chromosome:

chr17

Starnd:

-

Coordinate:

Start Site(bp):

7223308

End Site(bp):

7223330

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ACLY	chr17	41866917	41930542	-
ATXN7L3	chr17	44191805	44200113	-
CDC42EP2	chr11	65314866	65322417	+
CELSR2	chr1	109249539	109275751	+
DBNDD1	chr16	90004871	90020128	-
DCAF15	chr19	13952492	13961449	+
FBXL19	chr16	30923055	30948783	+
LNPEP	chr5	96935394	97037513	+
MAPKAPK2	chr1	206684944	206734283	+
MXD4	chr4	2247432	2262109	-
NACC1	chr19	13116862	13141147	+
PDRG1	chr20	31944337	31952046	-
SMAD7	chr18	48919853	48952052	-
SPTBN2	chr11	66685248	66729226	-
SYVN1	chr11	65121780	65134533	-
TAGLN	chr11	117199370	117207464	+
TNFRSF10B	chr8	23020133	23069031	-
TULP4	chr6	158232236	158511828	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001727	chr7	99621041	99621930	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC040162.3	chr16	67882461	67886367	+
AC234582.1	chr1	155195004	155205495	+
KCNQ1OT1	chr11	2608328	2699994	-
LINC01521	chr22	31346777	31348719	+
MALAT1	chr11	65497688	65506516	+
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
SNHG22	chr18	49814023	49851059	+

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.