exRNAdisease

Entry Detail

General Information

Database ID:

exR0352363

RNA Name:

hsa-miR-338-3p

RNA Type:

miRNA

Chromosome:

chr17

Starnd:

-

Coordinate:

Start Site(bp):

81125887

End Site(bp):

81125908

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ADCY9	chr16	3953387	4116442	-
ARPC1B	chr7	99374249	99394816	+
CALU	chr7	128739292	128773400	+
CDT1	chr16	88803789	88809258	+
ENSA	chr1	150600851	150629612	-
ERG28	chr14	75649791	75660876	-
GTSE1	chr22	46296870	46330810	+
KDSR	chr18	63327726	63367228	-
NONO	chrX	71283192	71301168	+
PALLD	chr4	168497052	168928457	+
PURB	chr7	44876299	44885530	-
RAB14	chr9	121178133	121223014	-
TANC2	chr17	63009556	63427699	+
TRIM33	chr1	114392790	114511203	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001025	chr2	69565029	69565697	-
hsa_circ_0000284	chr11	33307958	33309057	+
hsa_circ_0001085	chr2	191765289	191789319	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC008738.7	chr19	33207129	33207639	+
AC109460.3	chr16	28974804	28990775	+
KCNQ1OT1	chr11	2608328	2699994	-
LINC00943	chr12	126723412	126749027	+
MALAT1	chr11	65497688	65506516	+
NEAT1	chr11	65422774	65445540	+
OIP5-AS1	chr15	41283990	41309737	+
SDCBP2-AS1	chr20	1325405	1378735	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.