exRNAdisease

Entry Detail

General Information

Database ID:

exR0352379

RNA Name:

hsa-miR-361-3p

RNA Type:

miRNA

Chromosome:

chrX

Starnd:

-

Coordinate:

Start Site(bp):

85903641

End Site(bp):

85903663

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ADD1	chr4	2843857	2930076	+
ATP2A3	chr17	3923870	3964464	-
C6orf89	chr6	36871870	36928964	+
CBX2	chr17	79778148	79787983	+
CCDC88C	chr14	91271323	91417844	-
CDC25B	chr20	3786772	3806121	+
CTDSP2	chr12	57819927	57846729	-
CTSB	chr8	11842524	11869448	-
EGR1	chr5	138465479	138469303	+
FOXP4	chr6	41546426	41602384	+
HYOU1	chr11	119044188	119057227	-
IGF2BP1	chr17	48997385	49056145	+
NACC1	chr19	13116862	13141147	+
NPTN	chr15	73560014	73634134	-
PRMT1	chr19	49675786	49689029	+
SH2B1	chr16	28846600	28874212	+
SPTBN2	chr11	66685248	66729226	-
TNFAIP3	chr6	137867214	137883312	+
UBTF	chr17	44205033	44221626	-
VCL	chr10	73995193	74121363	+
ZBTB7A	chr19	4043303	4066899	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000921	chr19	30476129	30477324	+
hsa_circ_0000032	chr1	25666964	25669564	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC016876.2	chr17	7581964	7584086	-
AC092127.1	chr16	85592266	85595720	+
KCNQ1OT1	chr11	2608328	2699994	-
MALAT1	chr11	65497688	65506516	+
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
SNHG1	chr11	62851984	62855953	-

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.