exRNAdisease

Entry Detail

General Information

Database ID:

exR0352401

RNA Name:

hsa-miR-3652

RNA Type:

miRNA

Chromosome:

chr12

Starnd:

+

Coordinate:

Start Site(bp):

103930425

End Site(bp):

103930442

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ATP5MC3	chr2	175176258	175184607	-
GANAB	chr11	62624826	62646726	-
HDLBP	chr2	241227264	241317061	-
PGRMC1	chrX	119236245	119244466	+
PTMA	chr2	231706895	231713541	+
RAB15	chr14	64945814	64973226	-
AC099811.2	chr17	42119674	42154916	-
AP2A1	chr19	49766968	49807113	+
AP2M1	chr3	184174689	184184091	+
ARHGAP33	chr19	35774532	35788822	+
BDNF	chr11	27654893	27722058	-
BRI3	chr7	98252379	98310441	+
CCT6A	chr7	56051685	56063989	+
FKBP8	chr19	18531751	18544077	-
GATC	chr12	120446444	120463749	+
GDF11	chr12	55743122	55757264	+
HLA-DRA	chr6	32439878	32445046	+
HSP90B1	chr12	103930107	103953645	+
MIB2	chr1	1615415	1630610	+
RAB5C	chr17	42124976	42155044	-
SF3A2	chr19	2236824	2248655	+
SFPQ	chr1	35176378	35193145	-
WASF1	chr6	110099819	110180004	-
WBP11	chr12	14784582	14803486	-

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC022819.1	chr15	99157231	99161140	-
AL591742.2	chr1	114032393	114034511	+

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.