exRNAdisease

Entry Detail

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General Information

Database ID: exR0352423 RNA Name: hsa-miR-3681-3p RNA Type: miRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 12199174 End Site(bp): 12199195 External Links: hsa-miR-3681-3p

Disease Information

Disease Name: Polycystic Ovary Syndrome Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D011085 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID: GSE86241 Description: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Experimental Design: Disease vs Control Case Disease Type: Polycystic Ovary Syndrome Case Disease SubType: NA Case Sample: Polycystic Ovary Syndrome Control Sample: Control Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: NA miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000384 chr12 27867712 27877119 + hsa_circ_0000942 chr19 46020920 46021352 + hsa_circ_0001865 chr9 86292641 86293514 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012181.2 chr16 56940278 56941342 + AC021078.1 chr5 149494314 149504670 - AC021092.1 chr19 44103007 44113183 - AC239868.1 chr1 149861271 149862504 + ARHGAP27P1-BPTFP1-KPNA2P3 chr17 64749663 64781707 - CYTOR chr2 87454781 87636740 + KCNQ1OT1 chr11 2608328 2699994 - MIR4435-2HG chr2 111006015 111523376 - MIR497HG chr17 7015818 7019659 - NEAT1 chr11 65422774 65445540 + OIP5-AS1 chr15 41283990 41309737 + SNHG16 chr17 76557764 76565348 + SNHG22 chr18 49814023 49851059 + TUG1 chr22 30969245 30979395 + Display:

Experiment Detail

GEO ID: GSE86241 Sample Source: Blood Source Fraction: Serum Platform: GPL21575 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1951 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea). RNA library preparation protocol: Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID: 27677182 Title: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Author: Song DK, Sung YA, Lee H Journal: PLoS One. 2016 Sep 27;11(9):e0163756. Description: The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.