Entry Detail



General Information

Database ID:exR0352461
RNA Name:hsa-miR-379-5p
RNA Type:miRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):101022071End Site(bp):101022091
External Links:hsa-miR-379-5p



Disease Information

Disease Name:Polycystic Ovary Syndrome
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D011085
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary



Expression Detail

GEO ID:GSE86241
Description:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:Disease vs Control
Case Disease Type:Polycystic Ovary Syndrome
Case Disease SubType:NA
Case Sample:Polycystic Ovary Syndrome
Control Sample:Control
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ATF7
chr12
53507856
53626410
-
CBX5
chr12
54230942
54280133
-
CHP1
chr15
41230839
41281887
+
DCUN1D4
chr4
51843000
51916837
+
EDA2R
chrX
66595637
66639298
-
MAP3K21
chr1
233327724
233385148
+
NONO
chrX
71283192
71301168
+
NRARP
chr9
137299631
137302271
-
PLD3
chr19
40348456
40380439
+
SIN3A
chr15
75369379
75455842
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000741
chr17
7402357
7402810
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
NEAT1
chr11
65422774
65445540
+
SCARNA9
chr11
93721513
93721865
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE86241
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21575
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1951
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.



Reference

PMID:27677182
Title:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:Song DK, Sung YA, Lee H
Journal:PLoS One. 2016 Sep 27;11(9):e0163756.
Description:The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.