exRNAdisease

Entry Detail

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General Information

Database ID: exR0352639 RNA Name: hsa-miR-4524b-5p RNA Type: miRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 69099570 End Site(bp): 69099590 External Links: hsa-miR-4524b-5p

Disease Information

Disease Name: Polycystic Ovary Syndrome Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D011085 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID: GSE86241 Description: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Experimental Design: Disease vs Control Case Disease Type: Polycystic Ovary Syndrome Case Disease SubType: NA Case Sample: Polycystic Ovary Syndrome Control Sample: Control Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: NA miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000540 chr14 55799534 55821940 + hsa_circ_0001731 chr7 100731990 100738448 + hsa_circ_0001723 chr7 91924202 91948826 + hsa_circ_0001159 chr20 40161688 40179999 - hsa_circ_0001699 chr7 40027197 40041630 + hsa_circ_0000826 chr18 9182379 9221997 + hsa_circ_0001263 chr3 5215701 5216099 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004069.1 chr4 105137280 105140619 - AC009022.1 chr16 69976297 70065948 - AC021078.1 chr5 149494314 149504670 - AC079781.5 chr7 97851688 97972985 - AC114980.1 chr5 93860669 93863825 - AL049840.4 chr14 103694516 103695050 - AP000317.2 chr21 34073592 34360033 + KCNQ1OT1 chr11 2608328 2699994 - LINC00662 chr19 27681072 27794005 - LINC01184 chr5 127939152 128083172 - MALAT1 chr11 65497688 65506516 + MCM3AP-AS1 chr21 46229196 46259390 + NUTM2A-AS1 chr10 87201647 87342612 - NUTM2B-AS1 chr10 79661394 79826594 - OIP5-AS1 chr15 41283990 41309737 + RRN3P2 chr16 29074976 29116718 + SNHG1 chr11 62851984 62855953 - SNHG16 chr17 76557764 76565348 + ZSCAN16-AS1 chr6 28015122 28137293 - Display:

Experiment Detail

GEO ID: GSE86241 Sample Source: Blood Source Fraction: Serum Platform: GPL21575 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1951 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea). RNA library preparation protocol: Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID: 27677182 Title: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Author: Song DK, Sung YA, Lee H Journal: PLoS One. 2016 Sep 27;11(9):e0163756. Description: The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.