Entry Detail



General Information

Database ID:exR0352843
RNA Name:hsa-miR-492
RNA Type:miRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):94834427End Site(bp):94834449
External Links:hsa-miR-492



Disease Information

Disease Name:Polycystic Ovary Syndrome
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D011085
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary



Expression Detail

GEO ID:GSE86241
Description:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:Disease vs Control
Case Disease Type:Polycystic Ovary Syndrome
Case Disease SubType:NA
Case Sample:Polycystic Ovary Syndrome
Control Sample:Control
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
DYRK1A
chr21
37365573
37526358
+
KMT5A
chr12
123383773
123409353
+
NASP
chr1
45583846
45618904
+
ACAA2
chr18
49782164
49813953
-
ARL6IP1
chr16
18791669
18801572
-
EPCAM
chr2
47345158
47387601
+
GOPC
chr6
117560269
117602542
-
KRT19
chr17
41523617
41528308
-
RPS12
chr6
132814569
132817564
+
RPS16
chr19
39433137
39435949
-
SLC18B1
chr6
132769370
132813339
-
SLC20A1
chr2
112645939
112663825
+
TRMT44
chr4
8436140
8493531
+
UBC
chr12
124911604
124917368
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:GSE86241
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21575
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1951
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.



Reference

PMID:27677182
Title:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:Song DK, Sung YA, Lee H
Journal:PLoS One. 2016 Sep 27;11(9):e0163756.
Description:The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.