exRNAdisease

Entry Detail

General Information

Database ID:

exR0352882

RNA Name:

hsa-miR-5094

RNA Type:

miRNA

Chromosome:

chr15

Starnd:

-

Coordinate:

Start Site(bp):

89850690

End Site(bp):

89850711

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ZNHIT3	chr17	36486629	36499310	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001454	chr4	154524454	154533552	+
hsa_circ_0001005	chr2	53921020	53978078	-
hsa_circ_0000384	chr12	27867712	27877119	+
hsa_circ_0001159	chr20	40161688	40179999	-
hsa_circ_0000698	chr16	47531309	47549512	+
hsa_circ_0001445	chr4	144464661	144465125	+
hsa_circ_0000943	chr19	47421744	47440665	+
hsa_circ_0001667	chr7	810107	814799	+
hsa_circ_0001376	chr3	194169185	194175121	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC074117.1	chr2	27356246	27367622	+
AL356488.2	chr1	109100193	109100619	+
AL359091.1	chr9	128392007	128393510	-
DSCAM-AS1	chr21	40383083	40385358	+
FTX	chrX	73940435	74293574	-
GAS5	chr1	173858559	173868882	-
NEAT1	chr11	65422774	65445540	+
NUTM2B-AS1	chr10	79661394	79826594	-
PDCD4-AS1	chr10	110869868	110872233	-
SNHG3	chr1	28505980	28510892	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.