Entry Detail



General Information

Database ID:exR0353017
RNA Name:hsa-miR-556-5p
RNA Type:miRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):162342561End Site(bp):162342582
External Links:hsa-miR-556-5p



Disease Information

Disease Name:Polycystic Ovary Syndrome
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D011085
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary



Expression Detail

GEO ID:GSE86241
Description:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:Disease vs Control
Case Disease Type:Polycystic Ovary Syndrome
Case Disease SubType:NA
Case Sample:Polycystic Ovary Syndrome
Control Sample:Control
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MXD1
chr2
69897688
69942945
+
OSR2
chr8
98944403
98952104
+
SOX13
chr1
204073115
204127743
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001673
chr7
6085701
6089676
-
hsa_circ_0000711
chr16
68155889
68160513
+
hsa_circ_0001168
chr20
47691321
47707559
+
hsa_circ_0000799
chr17
65941524
65972074
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020978.7
chr16
68224713
68227734
+
AC023509.1
chr12
53441741
53467528
+
AL355075.4
chr14
20343048
20343685
-
KCNQ1OT1
chr11
2608328
2699994
-
LINC00265
chr7
39733430
39793092
+
NEAT1
chr11
65422774
65445540
+
SNHG1
chr11
62851984
62855953
-
Display:



Experiment Detail

GEO ID:GSE86241
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21575
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1951
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.



Reference

PMID:27677182
Title:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:Song DK, Sung YA, Lee H
Journal:PLoS One. 2016 Sep 27;11(9):e0163756.
Description:The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.