exRNAdisease

Entry Detail

General Information

Database ID:

exR0353132

RNA Name:

hsa-miR-624-3p

RNA Type:

miRNA

Chromosome:

chr14

Starnd:

-

Coordinate:

Start Site(bp):

31014669

End Site(bp):

31014689

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
CBL	chr11	119206298	119313926	+
GPCPD1	chr20	5544439	5611006	-
MDK	chr11	46380756	46383837	+
PTPA	chr9	129110950	129148946	+
SOBP	chr6	107490106	107661306	+
VANGL1	chr1	115641970	115698224	+
WSB2	chr12	118032694	118062430	-
ZBTB5	chr9	37438102	37465450	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000095	chr1	95609446	95616975	+
hsa_circ_0000698	chr16	47531309	47549512	+
hsa_circ_0000552	chr14	71880664	71948928	+
hsa_circ_0001376	chr3	194169185	194175121	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC005034.3	chr2	75697583	75697996	+
AC010327.5	chr19	55216660	55221616	+
AC016876.2	chr17	7581964	7584086	-
AL162171.3	chr14	88589231	88592408	+
ARHGAP27P1-BPTFP1-KPNA2P3	chr17	64749663	64781707	-
DHRS4-AS1	chr14	23938219	24052555	-
MIR17HG	chr13	91347820	91354579	+
NEAT1	chr11	65422774	65445540	+
SNHG1	chr11	62851984	62855953	-
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.