exRNAdisease

Entry Detail

General Information

Database ID:

exR0353194

RNA Name:

hsa-miR-663a

RNA Type:

miRNA

Chromosome:

chr20

Starnd:

-

Coordinate:

Start Site(bp):

26208243

End Site(bp):

26208264

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
COL6A2	chr21	46098112	46132848	+
KLC2	chr11	66257294	66267860	+
REXO1	chr19	1815248	1848483	-
MIDN	chr19	1248553	1259140	+
STK35	chr20	2101827	2177038	+
MIGA2	chr9	129036621	129072082	+
SRPRA	chr11	126262938	126269144	-
KDM2A	chr11	67119263	67258082	+
JUNB	chr19	12791486	12793315	+
GNB1	chr1	1785285	1891117	-
SYVN1	chr11	65121780	65134533	-
SCN1B	chr19	35030470	35040449	+
SMAD3	chr15	67063763	67195169	+
HIF1AN	chr10	100529072	100559998	+
TNRC6A	chr16	24610209	24827632	+
ARHGAP1	chr11	46677080	46700619	-
ARL8A	chr1	202133404	202144743	-
PPDPF	chr20	63520765	63522206	+
KMT5A	chr12	123383773	123409353	+
RTL8A	chrX	135050932	135052196	-
SOX12	chr20	325595	330224	+
CYB5R3	chr22	42617840	42649392	-
PRR12	chr19	49591182	49626439	+
CAPN15	chr16	527712	554636	+
DMWD	chr19	45782947	45792845	-
BOC	chr3	113211003	113287459	+
FAM83H	chr8	143723933	143738234	-
CLSTN1	chr1	9728926	9823984	-
CALR	chr19	12938578	12944489	+
CMIP	chr16	81445170	81711762	+

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC008738.7	chr19	33207129	33207639	+
AC020928.2	chr19	36773712	36775908	-
AC069281.2	chr7	100572232	100578700	-
AC234582.1	chr1	155195004	155205495	+
AL137127.1	chr1	19072110	19075511	-
AL355075.4	chr14	20343048	20343685	-
AL356488.2	chr1	109100193	109100619	+
GAS5	chr1	173858559	173868882	-
MIR663AHG	chr20	26167817	26251546	-
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
SNHG25	chr17	64145970	64146476	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.