exRNAdisease

Entry Detail

---



General Information

Database ID: exR0353386 RNA Name: hsa-miR-6838-5p RNA Type: miRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 44073407 End Site(bp): 44073428 External Links: hsa-miR-6838-5p

Disease Information

Disease Name: Polycystic Ovary Syndrome Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D011085 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID: GSE86241 Description: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Experimental Design: Disease vs Control Case Disease Type: Polycystic Ovary Syndrome Case Disease SubType: NA Case Sample: Polycystic Ovary Syndrome Control Sample: Control Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: NA miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000540 chr14 55799534 55821940 + hsa_circ_0001005 chr2 53921020 53978078 - hsa_circ_0001723 chr7 91924202 91948826 + hsa_circ_0000458 chr12 124071293 124074996 + hsa_circ_0001699 chr7 40027197 40041630 + hsa_circ_0001387 chr4 1902352 1936989 + hsa_circ_0001168 chr20 47691321 47707559 + hsa_circ_0000552 chr14 71880664 71948928 + hsa_circ_0000038 chr1 28800065 28802803 + hsa_circ_0000652 chr15 90984737 90986710 + hsa_circ_0001472 chr5 36953719 36976504 + hsa_circ_0001263 chr3 5215701 5216099 + hsa_circ_0000799 chr17 65941524 65972074 + hsa_circ_0001164 chr20 45891031 45923523 - hsa_circ_0000032 chr1 25666964 25669564 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC003092.1 chr7 94022833 94066661 + NUTM2B-AS1 chr10 79661394 79826594 - LINC02035 chr3 122886941 122892416 + AL031282.2 chr1 1702736 1737688 - AC009022.1 chr16 69976297 70065948 - AC020978.7 chr16 68224713 68227734 + MIR29B2CHG chr1 207801518 207879115 - AC002470.2 chr22 20979462 20998121 + LINC01184 chr5 127939152 128083172 - SNHG12 chr1 28578538 28583132 - XIST chrX 73820649 73852723 - AC021078.1 chr5 149494314 149504670 - AC021092.1 chr19 44103007 44113183 - AL359924.1 chr1 237862175 237928321 + MIR497HG chr17 7015818 7019659 - HCG18 chr6 30286690 30327382 - LINC00649 chr21 33915534 33977691 + SNHG25 chr17 64145970 64146476 + AC079781.5 chr7 97851688 97972985 - AP000317.2 chr21 34073592 34360033 + AC114980.1 chr5 93860669 93863825 - NEAT1 chr11 65422774 65445540 + SNHG16 chr17 76557764 76565348 + LINC00662 chr19 27681072 27794005 - MIR503HG chrX 134543119 134546642 - STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + AL391244.1 chr1 1420245 1422691 + SNHG1 chr11 62851984 62855953 - MCM3AP-AS1 chr21 46229196 46259390 + MZF1-AS1 chr19 58559129 58574797 + Display:

Experiment Detail

GEO ID: GSE86241 Sample Source: Blood Source Fraction: Serum Platform: GPL21575 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1951 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea). RNA library preparation protocol: Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID: 27677182 Title: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Author: Song DK, Sung YA, Lee H Journal: PLoS One. 2016 Sep 27;11(9):e0163756. Description: The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.