exRNAdisease

Entry Detail

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General Information

Database ID: exR0353472 RNA Name: hsa-miR-708-5p RNA Type: miRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 79402077 End Site(bp): 79402099 External Links: hsa-miR-708-5p

Disease Information

Disease Name: Polycystic Ovary Syndrome Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D011085 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID: GSE86241 Description: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Experimental Design: Disease vs Control Case Disease Type: Polycystic Ovary Syndrome Case Disease SubType: NA Case Sample: Polycystic Ovary Syndrome Control Sample: Control Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANKRD52 chr12 56237807 56258384 - TUB chr11 8019244 8106112 + ERG28 chr14 75649791 75660876 - KIAA1522 chr1 32741830 32774970 + RGMA chr15 93035273 93089204 - RARG chr12 53210567 53232980 - GPCPD1 chr20 5544439 5611006 - ZBTB7B chr1 155002630 155018522 + GLYR1 chr16 4803203 4847288 - SMARCD1 chr12 50085200 50100707 + UBE2Z chr17 48908407 48929056 + SEH1L chr18 12947133 12987536 + LONRF2 chr2 100271875 100322501 - ENSA chr1 150600851 150629612 - PTMS chr12 6765516 6770952 + ATXN2L chr16 28823035 28837237 + FAM102A chr9 127940582 127980989 - TOB2 chr22 41433494 41446801 - SLC31A1 chr9 113221544 113264492 + PTPN23 chr3 47381011 47413435 + TEX261 chr2 70985942 70994873 - E2F4 chr16 67192155 67198918 + N4BP1 chr16 48538726 48620148 - FOXK1 chr7 4682295 4771442 + DYRK1A chr21 37365573 37526358 + E2F6 chr2 11444375 11466177 - CPSF2 chr14 92121969 92172145 + NAPA chr19 47487637 47515091 - MAPK1 chr22 21754500 21867680 - SMYD1 chr2 88067825 88113384 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000417 chr12 69644908 69656342 + hsa_circ_0001146 chr20 34241449 34246936 - hsa_circ_0001164 chr20 45891031 45923523 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009065.4 chr16 2119207 2120248 + AC016876.2 chr17 7581964 7584086 - AC026362.1 chr12 122975320 122982907 + AC118758.3 chr7 56809214 56848800 - MALAT1 chr11 65497688 65506516 + NEAT1 chr11 65422774 65445540 + OIP5-AS1 chr15 41283990 41309737 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE86241 Sample Source: Blood Source Fraction: Serum Platform: GPL21575 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1951 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea). RNA library preparation protocol: Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID: 27677182 Title: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Author: Song DK, Sung YA, Lee H Journal: PLoS One. 2016 Sep 27;11(9):e0163756. Description: The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.