exRNAdisease

Entry Detail

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General Information

Database ID: exR0353993 RNA Name: hsa-miR-1244 RNA Type: miRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 231713368 End Site(bp): 231713393 External Links: hsa-miR-1244

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE93850 Description: Serum miRNAs in Patients with Glioblastoma Multiforme Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 22 Number of Control: 8 Number of Samples: 30

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RHOA chr3 49359145 49412998 - CPNE3 chr8 86514435 86561498 + KIAA1191 chr5 176346062 176361807 - ZMYM4 chr1 35268709 35422058 + CCT2 chr12 69585426 69601570 + AL590764.2 chrX 71103987 71111575 - RPS5 chr19 58386400 58394806 + UBA2 chr19 34428352 34471251 + CDC42EP3 chr2 37641882 37738468 - EEF1G chr11 62559596 62574086 - GAK chr4 849276 932373 - SPIN1 chr9 88388430 88478694 + ERLIN1 chr10 100150094 100186033 - MT-CO3 chrMT 9207 9990 + HNRNPU chr1 244840638 244864560 - TOLLIP chr11 1274371 1309654 - MLF2 chr12 6747996 6767475 - CCDC18 chr1 93179919 93278730 + MBD3 chr19 1573596 1592865 - RPS2 chr16 1962058 1964841 - PTMA chr2 231706895 231713541 + UBC chr12 124911604 124917368 - OAS2 chr12 112978395 113011723 + APELA chr4 164877178 164898965 + SLC7A1 chr13 29509414 29595688 - ARHGDIB chr12 14942031 14961728 - ARMT1 chr6 151452258 151470101 + AP002990.1 chr11 62559603 62591531 - B2M chr15 44711487 44718877 + RFWD3 chr16 74621399 74666877 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE93850 Sample Source: Blood Source Fraction: Serum Platform: GPL22948 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1032 Sample treatment protocol: NA RNA Extract protocol: Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada) RNA library preparation protocol: 0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.

Reference

PMID: 28931080 Title: Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma Author: Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX Journal: PLoS One. 2017 Sep 20;12(9):e0184969. Description: we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.