Entry Detail


General Information

Database ID:exR0354096
RNA Name:hsa-miR-142-5p
RNA Type:miRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):58331283End Site(bp):58331303
External Links:hsa-miR-142-5p



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE93850
Description:Serum miRNAs in Patients with Glioblastoma Multiforme
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:22
Number of Control:8
Number of Samples:30





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BBS10
chr12
76344474
76348415
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000698
chr16
47531309
47549512
+
hsa_circ_0001085
chr2
191765289
191789319
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC087477.2
chr15
96354237
96405235
+
AC093010.3
chr3
114314501
114329714
-
AC135050.6
chr16
31122235
31124064
+
AC243964.3
chr19
44631573
44725217
-
AL158206.1
chr9
19453209
19455173
+
CKMT2-AS1
chr5
81201341
81301565
-
EPB41L4A-AS1
chr5
112160526
112164818
+
ERICD
chr8
140636281
140638283
+
FGD5-AS1
chr3
14920347
14948424
-
NEAT1
chr11
65422774
65445540
+
OIP5-AS1
chr15
41283990
41309737
+
SNHG5
chr6
85650491
85678932
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE93850
Sample Source:Blood
Source Fraction:Serum
Platform:GPL22948
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1032
Sample treatment protocol:NA
RNA Extract protocol:Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada)
RNA library preparation protocol:0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.



Reference

PMID:28931080
Title:Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma
Author:Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX
Journal:PLoS One. 2017 Sep 20;12(9):e0184969.
Description:we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.