Entry Detail



General Information

Database ID:exR0354119
RNA Name:hsa-miR-151a-3p
RNA Type:miRNA
Chromosome:chr8
Starnd:-
Coordinate:
Start Site(bp):140732587End Site(bp):140732607
External Links:hsa-miR-151a-3p



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE93850
Description:Serum miRNAs in Patients with Glioblastoma Multiforme
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:22
Number of Control:8
Number of Samples:30





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACP1
chr2
264140
278283
+
PCDHA1
chr5
140786136
141012347
+
PCDHA10
chr5
140855883
141012347
+
PCDHA11
chr5
140868183
141012344
+
PCDHA12
chr5
140875302
141012347
+
PCDHA13
chr5
140882124
141012347
+
PCDHA2
chr5
140794852
141012347
+
PCDHA3
chr5
140801028
141012347
+
PCDHA4
chr5
140806929
141012347
+
PCDHA5
chr5
140821604
141012347
+
PCDHA6
chr5
140827958
141012347
+
PCDHA7
chr5
140834248
141012347
+
PCDHA8
chr5
140841187
141012347
+
PCDHA9
chr5
140847463
141012344
+
PCDHAC1
chr5
140926369
141012344
+
PCDHAC2
chr5
140966470
141012347
+
STRBP
chr9
123109500
123268586
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC044784.1
chr10
8970125
8973468
+
AC104794.2
chr2
10083781
10086101
+
AL160006.1
chr1
110058340
110062555
+
SCARNA9
chr11
93721513
93721865
+
TUG1
chr22
30969245
30979395
+
Display:



Experiment Detail

GEO ID:GSE93850
Sample Source:Blood
Source Fraction:Serum
Platform:GPL22948
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1032
Sample treatment protocol:NA
RNA Extract protocol:Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada)
RNA library preparation protocol:0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.



Reference

PMID:28931080
Title:Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma
Author:Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX
Journal:PLoS One. 2017 Sep 20;12(9):e0184969.
Description:we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.