exRNAdisease

Entry Detail

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General Information

Database ID: exR0354308 RNA Name: hsa-miR-302c-3p RNA Type: miRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 112648366 End Site(bp): 112648388 External Links: hsa-miR-302c-3p

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE93850 Description: Serum miRNAs in Patients with Glioblastoma Multiforme Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 22 Number of Control: 8 Number of Samples: 30

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MTMR12 chr5 32226994 32312987 - TXNIP chr1 145992435 145996579 - CLU chr8 27596917 27614700 - MBP chr18 76978827 77133683 - CCNB1 chr5 69167135 69178245 + SETD7 chr4 139495941 139606699 - NUP153 chr6 17615035 17706834 - SEC16A chr9 136440096 136483759 - SLAIN2 chr4 48341529 48426201 + ZSCAN26 chr6 28267010 28278224 + CUL1 chr7 148697914 148801110 + TRA2A chr7 23504780 23532041 - TEFM chr17 30897336 30906238 - CCNG2 chr4 77157207 77433388 + CDK6 chr7 92604921 92836594 - FYCO1 chr3 45917899 45995824 - PSMD5 chr9 120815496 120842951 - MTFR2 chr6 136231024 136250335 - VRK1 chr14 96797382 96931722 + UGP2 chr2 63840940 63891562 + KMT5B chr11 68154863 68213828 - SEMA3C chr7 80742538 80922359 - COX7C chr5 86617928 86620962 + SRRT chr7 100875103 100888664 + BCL7A chr12 122019422 122062044 + PDXK chr21 43719094 43762307 + MOB1A chr2 74152528 74178898 - MSTO1 chr1 155610188 155614971 + NPC2 chr14 74476192 74494177 - CAMK2N1 chr1 20482391 20486210 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000943 chr19 47421744 47440665 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011503.2 chr19 23927788 23929287 + AC125257.1 chr17 41848518 41851447 - AL049840.4 chr14 103694516 103695050 - ARHGAP27P1-BPTFP1-KPNA2P3 chr17 64749663 64781707 - FGD5-AS1 chr3 14920347 14948424 - MIR17HG chr13 91347820 91354579 + NEAT1 chr11 65422774 65445540 + NORAD chr20 36045618 36051018 - SNHG16 chr17 76557764 76565348 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE93850 Sample Source: Blood Source Fraction: Serum Platform: GPL22948 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1032 Sample treatment protocol: NA RNA Extract protocol: Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada) RNA library preparation protocol: 0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.

Reference

PMID: 28931080 Title: Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma Author: Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX Journal: PLoS One. 2017 Sep 20;12(9):e0184969. Description: we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.