exRNAdisease

Entry Detail

---



General Information

Database ID: exR0354312 RNA Name: hsa-miR-302e RNA Type: miRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 7234771 End Site(bp): 7234787 External Links: hsa-miR-302e

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE93850 Description: Serum miRNAs in Patients with Glioblastoma Multiforme Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 22 Number of Control: 8 Number of Samples: 30

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ATP6V1B2 chr8 20197381 20226819 + BTN3A1 chr6 26402237 26415208 + CCSAP chr1 229321011 229343294 - CELF2 chr10 10798397 11336675 + CLCN6 chr1 11806096 11848079 + COL4A2 chr13 110305812 110513209 + CUL1 chr7 148697914 148801110 + KMT5B chr11 68154863 68213828 - MTMR12 chr5 32226994 32312987 - OCRL chrX 129539849 129592561 + PFN2 chr3 149964904 150050788 - PLAGL2 chr20 32192504 32207743 - PLEKHM1 chr17 45435900 45490749 - SEC16A chr9 136440096 136483759 - SLC7A2 chr8 17497088 17570573 + SYAP1 chrX 16719612 16765340 + TARDBP chr1 11012344 11026420 + TRIB1 chr8 125430358 125438403 + TXNIP chr1 145992435 145996579 - WASF3 chr13 26557683 26688948 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000943 chr19 47421744 47440665 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL049840.4 chr14 103694516 103695050 - ARHGAP27P1-BPTFP1-KPNA2P3 chr17 64749663 64781707 - FGD5-AS1 chr3 14920347 14948424 - MIR17HG chr13 91347820 91354579 + NEAT1 chr11 65422774 65445540 + SNHG16 chr17 76557764 76565348 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE93850 Sample Source: Blood Source Fraction: Serum Platform: GPL22948 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1032 Sample treatment protocol: NA RNA Extract protocol: Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada) RNA library preparation protocol: 0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.

Reference

PMID: 28931080 Title: Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma Author: Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX Journal: PLoS One. 2017 Sep 20;12(9):e0184969. Description: we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.