exRNAdisease

Entry Detail

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General Information

Database ID: exR0354422 RNA Name: hsa-miR-320b RNA Type: miRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 224257049 End Site(bp): 224257070 External Links: hsa-miR-320b

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE93850 Description: Serum miRNAs in Patients with Glioblastoma Multiforme Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 22 Number of Control: 8 Number of Samples: 30

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACAP2 chr3 195274745 195443044 - ASB1 chr2 238426742 238452250 + BLCAP chr20 37492472 37527931 - BTAF1 chr10 91923770 92030325 + CGN chr1 151510510 151538692 + CKAP5 chr11 46743048 46846308 - CRTC3 chr15 90529923 90645345 + FJX1 chr11 35618460 35620865 + GNAI2 chr3 50226292 50259362 + HECTD2 chr10 91409280 91514829 + IGF2BP3 chr7 23310209 23470491 - MAPKAPK2 chr1 206684944 206734283 + NR4A2 chr2 156324437 156342348 - PFN1 chr17 4945652 4949061 - SGK1 chr6 134169246 134318112 - SIN3A chr15 75369379 75455842 - SRSF7 chr2 38743599 38751494 - TRIM14 chr9 98069275 98119222 - ZCCHC2 chr18 62523025 62587709 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000417 chr12 69644908 69656342 + hsa_circ_0000540 chr14 55799534 55821940 + hsa_circ_0000095 chr1 95609446 95616975 + hsa_circ_0000744 chr17 15968183 15971435 - hsa_circ_0000652 chr15 90984737 90986710 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002044.1 chr16 73014319 73014476 - AC016876.2 chr17 7581964 7584086 - AC092718.4 chr16 81030770 81031485 + AL022311.1 chr22 37876148 37895563 + AL162258.1 chr1 153626332 153634340 - DLEU1 chr13 50082169 50906856 + GAS5 chr1 173858559 173868882 - LINC00641 chr14 21200079 21206900 - MALAT1 chr11 65497688 65506516 + MIR3142HG chr5 160438594 160487426 + NEAT1 chr11 65422774 65445540 + NR2F2-AS1 chr15 96110040 96327361 - OIP5-AS1 chr15 41283990 41309737 + SNHG1 chr11 62851984 62855953 - SNHG12 chr1 28578538 28583132 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE93850 Sample Source: Blood Source Fraction: Serum Platform: GPL22948 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1032 Sample treatment protocol: NA RNA Extract protocol: Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada) RNA library preparation protocol: 0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.

Reference

PMID: 28931080 Title: Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma Author: Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX Journal: PLoS One. 2017 Sep 20;12(9):e0184969. Description: we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.