exRNAdisease

Entry Detail

---



General Information

Database ID: exR0354427 RNA Name: hsa-miR-324-3p RNA Type: miRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 7223308 End Site(bp): 7223330 External Links: hsa-miR-324-3p

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE93850 Description: Serum miRNAs in Patients with Glioblastoma Multiforme Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 22 Number of Control: 8 Number of Samples: 30

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACLY chr17 41866917 41930542 - ATXN7L3 chr17 44191805 44200113 - CDC42EP2 chr11 65314866 65322417 + CELSR2 chr1 109249539 109275751 + DBNDD1 chr16 90004871 90020128 - DCAF15 chr19 13952492 13961449 + FBXL19 chr16 30923055 30948783 + LNPEP chr5 96935394 97037513 + MAPKAPK2 chr1 206684944 206734283 + MXD4 chr4 2247432 2262109 - NACC1 chr19 13116862 13141147 + PDRG1 chr20 31944337 31952046 - SMAD7 chr18 48919853 48952052 - SPTBN2 chr11 66685248 66729226 - SYVN1 chr11 65121780 65134533 - TAGLN chr11 117199370 117207464 + TNFRSF10B chr8 23020133 23069031 - TULP4 chr6 158232236 158511828 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001727 chr7 99621041 99621930 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC040162.3 chr16 67882461 67886367 + AC234582.1 chr1 155195004 155205495 + KCNQ1OT1 chr11 2608328 2699994 - LINC01521 chr22 31346777 31348719 + MALAT1 chr11 65497688 65506516 + NEAT1 chr11 65422774 65445540 + NORAD chr20 36045618 36051018 - SNHG22 chr18 49814023 49851059 + Display:

Experiment Detail

GEO ID: GSE93850 Sample Source: Blood Source Fraction: Serum Platform: GPL22948 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1032 Sample treatment protocol: NA RNA Extract protocol: Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada) RNA library preparation protocol: 0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.

Reference

PMID: 28931080 Title: Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma Author: Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX Journal: PLoS One. 2017 Sep 20;12(9):e0184969. Description: we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.