Entry Detail



General Information

Database ID:exR0354497
RNA Name:hsa-miR-382-5p
RNA Type:miRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):101054316End Site(bp):101054337
External Links:hsa-miR-382-5p



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE93850
Description:Serum miRNAs in Patients with Glioblastoma Multiforme
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:22
Number of Control:8
Number of Samples:30





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
APCDD1
chr18
10454635
10489949
+
BCAS2
chr1
114567557
114581629
-
BCL2L11
chr2
111119378
111168445
+
CAMTA1
chr1
6785454
7769706
+
COBLL1
chr2
164653624
164843679
-
ELK1
chrX
47635521
47650604
-
FOSL1
chr11
65892049
65900573
-
IGF2BP3
chr7
23310209
23470491
-
KMT5A
chr12
123383773
123409353
+
MAPRE2
chr18
34976928
35143470
+
NID1
chr1
235975830
236065109
-
PARM1
chr4
74933095
75050115
+
PDE8A
chr15
84980440
85139145
+
RAB18
chr10
27504174
27542237
+
SCAF11
chr12
45919131
45992120
-
SH3GL1
chr19
4360370
4400547
-
STEAP3
chr2
119223831
119265652
+
STK40
chr1
36339624
36385896
-
TAGLN
chr11
117199370
117207464
+
TUB
chr11
8019244
8106112
+
UBN2
chr7
139230356
139308236
+
WDR4
chr21
42843094
42879568
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC092718.4
chr16
81030770
81031485
+
AC126365.1
chr17
20788071
20789584
+
FGD5-AS1
chr3
14920347
14948424
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
TUG1
chr22
30969245
30979395
+
Display:



Experiment Detail

GEO ID:GSE93850
Sample Source:Blood
Source Fraction:Serum
Platform:GPL22948
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1032
Sample treatment protocol:NA
RNA Extract protocol:Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada)
RNA library preparation protocol:0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.



Reference

PMID:28931080
Title:Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma
Author:Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX
Journal:PLoS One. 2017 Sep 20;12(9):e0184969.
Description:we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.