Entry Detail


General Information

Database ID:exR0354702
RNA Name:hsa-miR-524-5p
RNA Type:miRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):53711017End Site(bp):53711038
External Links:hsa-miR-524-5p



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE93850
Description:Serum miRNAs in Patients with Glioblastoma Multiforme
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:22
Number of Control:8
Number of Samples:30





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
KLHL28
chr14
44924319
45042322
-
NEDD4
chr15
55826922
55993746
-
NR4A2
chr2
156324437
156342348
-
PKN2
chr1
88684222
88836255
+
SIK2
chr11
111602449
111730855
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000095
chr1
95609446
95616975
+
hsa_circ_0000284
chr11
33307958
33309057
+
hsa_circ_0001146
chr20
34241449
34246936
-
hsa_circ_0000799
chr17
65941524
65972074
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC008738.7
chr19
33207129
33207639
+
AC009022.1
chr16
69976297
70065948
-
AC021078.1
chr5
149494314
149504670
-
AC024940.6
chr12
31280422
31280895
-
AC068768.1
chr12
123262060
123262402
+
AC125257.1
chr17
41848518
41851447
-
AC239868.1
chr1
149861271
149862504
+
AL031595.3
chr22
44139365
44153626
+
AL137129.1
chr14
61734138
61776260
+
FGD5-AS1
chr3
14920347
14948424
-
GAS5
chr1
173858559
173868882
-
MCM3AP-AS1
chr21
46229196
46259390
+
MIR29B2CHG
chr1
207801518
207879115
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
PITPNA-AS1
chr17
1516931
1518096
+
SCARNA9
chr11
93721513
93721865
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE93850
Sample Source:Blood
Source Fraction:Serum
Platform:GPL22948
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1032
Sample treatment protocol:NA
RNA Extract protocol:Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada)
RNA library preparation protocol:0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.



Reference

PMID:28931080
Title:Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma
Author:Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX
Journal:PLoS One. 2017 Sep 20;12(9):e0184969.
Description:we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.