Entry Detail


General Information

Database ID:exR0354709
RNA Name:hsa-miR-532-5p
RNA Type:miRNA
Chromosome:chrX
Starnd:+
Coordinate:
Start Site(bp):50003167End Site(bp):50003188
External Links:hsa-miR-532-5p



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE93850
Description:Serum miRNAs in Patients with Glioblastoma Multiforme
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:22
Number of Control:8
Number of Samples:30





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AXL
chr19
41219223
41261766
+
CRIM1
chr2
36355778
36551135
+
DCTN4
chr5
150708440
150759109
-
LEPROTL1
chr8
30095408
30177208
+
LUZP1
chr1
23084023
23177808
-
MEX3A
chr1
156072013
156082465
-
PRRC1
chr5
127517609
127555089
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000787
chr17
54978779
54981849
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC079781.5
chr7
97851688
97972985
-
AL049796.1
chr1
93847174
93848939
+
AP000553.1
chr22
21652270
21670237
+
GAS5
chr1
173858559
173868882
-
KCNQ1OT1
chr11
2608328
2699994
-
RRN3P2
chr16
29074976
29116718
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE93850
Sample Source:Blood
Source Fraction:Serum
Platform:GPL22948
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1032
Sample treatment protocol:NA
RNA Extract protocol:Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada)
RNA library preparation protocol:0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.



Reference

PMID:28931080
Title:Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma
Author:Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX
Journal:PLoS One. 2017 Sep 20;12(9):e0184969.
Description:we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.