exRNAdisease

Entry Detail

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General Information

Database ID: exR0354831 RNA Name: hsa-miR-629-5p RNA Type: miRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 70079427 End Site(bp): 70079447 External Links: hsa-miR-629-5p

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE93850 Description: Serum miRNAs in Patients with Glioblastoma Multiforme Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 22 Number of Control: 8 Number of Samples: 30

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BAZ2A chr12 56595596 56636816 - CBX2 chr17 79778148 79787983 + CBX3 chr7 26201162 26213607 + COL4A1 chr13 110148963 110307157 - DENND5B chr12 31382226 31591136 - GRB10 chr7 50590063 50793462 - HDLBP chr2 241227264 241317061 - LDLR chr19 11089462 11133820 + MCM3 chr6 52264014 52284881 - MSI1 chr12 120341330 120369164 - NOLC1 chr10 102152176 102163871 + PA2G4 chr12 56104537 56113910 + PHF12 chr17 28905250 28951771 - PRR12 chr19 49591182 49626439 + RSU1 chr10 16590611 16817463 - SH3KBP1 chrX 19533977 19887600 - SH3PXD2A chr10 103594027 103855543 - TULP4 chr6 158232236 158511828 + UBN2 chr7 139230356 139308236 + WIPF2 chr17 40219304 40284136 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000384 chr12 27867712 27877119 + hsa_circ_0001230 chr22 38895404 38897285 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC021078.1 chr5 149494314 149504670 - NEAT1 chr11 65422774 65445540 + U62317.3 chr22 50597152 50597599 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE93850 Sample Source: Blood Source Fraction: Serum Platform: GPL22948 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1032 Sample treatment protocol: NA RNA Extract protocol: Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada) RNA library preparation protocol: 0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.

Reference

PMID: 28931080 Title: Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma Author: Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX Journal: PLoS One. 2017 Sep 20;12(9):e0184969. Description: we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.