exRNAdisease

Entry Detail

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General Information

Database ID: exR0354874 RNA Name: hsa-miR-671-5p RNA Type: miRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 151238449 End Site(bp): 151238471 External Links: hsa-miR-671-5p

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE93850 Description: Serum miRNAs in Patients with Glioblastoma Multiforme Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 22 Number of Control: 8 Number of Samples: 30

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RCOR1 chr14 102592649 102730561 + KIAA0232 chr4 6781375 6884170 + TAF8 chr6 42050513 42087461 + MAFG chr17 81918270 81927735 - DYRK1A chr21 37365573 37526358 + MED22 chr9 133338312 133348131 - KLC1 chr14 103561896 103714249 + CBX6 chr22 38861422 38872249 - SAMD4B chr19 39342396 39385710 + GTSE1 chr22 46296870 46330810 + SETD5 chr3 9397615 9479240 + CREG1 chr1 167529117 167553805 - IRS2 chr13 109752695 109786583 - SCAMP3 chr1 155255979 155262430 - CCDC6 chr10 59788747 59906556 - BAZ2A chr12 56595596 56636816 - WDR82 chr3 52254434 52288020 - TOMM6 chr6 41787662 41789898 + FAM219A chr9 34398184 34458570 - STAT3 chr17 42313324 42388568 - UHRF1BP1 chr6 34792015 34883138 + AL365205.1 chr6 41780349 41790141 + NACC1 chr19 13116862 13141147 + SMAD3 chr15 67063763 67195169 + WDTC1 chr1 27234632 27308636 + IL1R1 chr2 102064544 102179874 + PTPRU chr1 29236516 29326813 + GLYR1 chr16 4803203 4847288 - APLP2 chr11 130068147 130144811 + CHTF8 chr16 69118010 69132578 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC067930.1 chr8 143579636 143580670 + AC145207.5 chr17 81878425 81881106 - AL022311.1 chr22 37876148 37895563 + AL137127.1 chr1 19072110 19075511 - H19 chr11 1995176 2001470 - KCNQ1OT1 chr11 2608328 2699994 - LINC01278 chrX 63222993 63561095 - MIR29B2CHG chr1 207801518 207879115 - NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE93850 Sample Source: Blood Source Fraction: Serum Platform: GPL22948 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1032 Sample treatment protocol: NA RNA Extract protocol: Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada) RNA library preparation protocol: 0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.

Reference

PMID: 28931080 Title: Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma Author: Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX Journal: PLoS One. 2017 Sep 20;12(9):e0184969. Description: we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.