Entry Detail


General Information

Database ID:exR0354941
RNA Name:hsa-miR-942-5p
RNA Type:miRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):117094655End Site(bp):117094676
External Links:hsa-miR-942-5p



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE93850
Description:Serum miRNAs in Patients with Glioblastoma Multiforme
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:22
Number of Control:8
Number of Samples:30





Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000910
chr19
17311101
17311638
+
hsa_circ_0000943
chr19
47421744
47440665
+
hsa_circ_0001387
chr4
1902352
1936989
+
hsa_circ_0000038
chr1
28800065
28802803
+
hsa_circ_0000799
chr17
65941524
65972074
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AL139260.2
chr1
38839333
38874494
-
AL162426.1
chr9
127690098
127690840
-
AL359924.1
chr1
237862175
237928321
+
KCNQ1OT1
chr11
2608328
2699994
-
LINC00943
chr12
126723412
126749027
+
MALAT1
chr11
65497688
65506516
+
MIR497HG
chr17
7015818
7019659
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
NUTM2A-AS1
chr10
87201647
87342612
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE93850
Sample Source:Blood
Source Fraction:Serum
Platform:GPL22948
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1032
Sample treatment protocol:NA
RNA Extract protocol:Serum total RNA was isolated from serum samples using the Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) (Norgen Biotek Corporation, Thorold, Ontario, Canada)
RNA library preparation protocol:0.3ug of total RNA of intrahepatic cholangiocarcinoma/normal intrahepatic bile duct tissue was employed with 100 nmol/L of pCp-DY547 (Dharmacon, Lafayette, CO, USA) and 15 Units of T4 RNA ligase (USB, Cleveland, Oh, USA) in a total reaction volume of 20 ul at 16°C overnight.



Reference

PMID:28931080
Title:Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma
Author:Wang ZQ, Zhang MY, Deng ML, Weng NQ, Wang HY,Wu SX
Journal:PLoS One. 2017 Sep 20;12(9):e0184969.
Description:we investigated whether 3 of the 19 miRNAs in serum could be used as prognostic biomarkers for patients with GBM.