exRNAdisease

Entry Detail

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General Information

Database ID: exR0355360 RNA Name: HOTAIR RNA Type: lncRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 53962308 End Site(bp): 53974956 External Links: ENSG00000228630

Disease Information

Disease Name: Rheumatoid Arthritis Disease Category: Musculoskeletal Diseases MeSH ID: D001172 Type: Diseases Category/Musculoskeletal Diseases Alias: Arthritis, Rheumatoid//Rheumatoid Arthritis

Expression Detail

GEO ID: GSE94519 Description: Long noncoding RNAs expression profile in patients with rheumatoid arthritis Experimental Design: Disease vs Control Case Disease Type: Rheumatoid Arthritis Case Disease SubType: NA Case Sample: Rheumatoid Arthritis Control Sample: Healthy Number of Case: 3 Number of Control: 3 Number of Samples: 6

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-17-5p chr13 91350618 91350640 + hsa-miR-20a-5p chr13 91351072 91351094 + hsa-miR-93-5p chr7 100093815 100093837 - hsa-miR-106a-5p chrX 134170244 134170266 - hsa-miR-126-5p chr9 136670616 136670636 + hsa-miR-106b-5p chr7 100094043 100094063 - hsa-miR-20b-5p chrX 134169850 134169872 - hsa-miR-519c-3p chr19 53686522 53686543 + hsa-miR-526b-3p chr19 53694443 53694464 + hsa-miR-519b-3p chr19 53695263 53695284 + hsa-miR-519d-3p chr19 53713400 53713421 + hsa-miR-520g-3p chr19 53722220 53722243 + hsa-miR-520h chr19 53742566 53742587 + hsa-miR-519a-3p chr19 53762397 53762418 + hsa-miR-1277-5p chrX 118386401 118386424 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE94519 Sample Source: Blood Source Fraction: Serum Platform: GPL20115 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1224 Sample treatment protocol: All blood samples were separately collected and sequentially centrifuged at 2000 rpm for 10 min. The cell-free serum from the supernatant was stored at -80°C for further detection. RNA Extract protocol: RNA was prepared using the Versagene Blood RNA Purification kit (Gentra Systems, Minneapolis MN). RNA library preparation protocol: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the One-Color Low RNA Input Linear Amplification PLUS kit (Agilent) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA