exRNAdisease

Entry Detail

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General Information

Database ID: exR0356029 RNA Name: TERC RNA Type: lncRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 169764520 End Site(bp): 169765060 External Links: ENSG00000270141

Disease Information

Disease Name: Rheumatoid Arthritis Disease Category: Musculoskeletal Diseases MeSH ID: D001172 Type: Diseases Category/Musculoskeletal Diseases Alias: Arthritis, Rheumatoid//Rheumatoid Arthritis

Expression Detail

GEO ID: GSE94519 Description: Long noncoding RNAs expression profile in patients with rheumatoid arthritis Experimental Design: Disease vs Control Case Disease Type: Rheumatoid Arthritis Case Disease SubType: NA Case Sample: Rheumatoid Arthritis Control Sample: Healthy Number of Case: 3 Number of Control: 3 Number of Samples: 6

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACLY chr17 41866917 41930542 - ACTB chr7 5527148 5563784 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-449a chr5 55170586 55170607 - hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-488-3p chr1 177029374 177029394 - hsa-miR-887-3p chr5 15935229 15935250 + hsa-miR-1249-3p chr22 45200958 45200979 - hsa-miR-3184-5p chr17 30117128 30117151 - hsa-miR-2277-5p chr5 93620748 93620771 - hsa-miR-4640-5p chr6 30890891 30890913 + hsa-miR-1343-3p chr11 34941888 34941909 + hsa-miR-4726-5p chr17 38719691 38719713 + hsa-miR-4766-5p chr22 40813927 40813947 - hsa-miR-6783-3p chr17 44934618 44934639 - hsa-miR-6835-3p chr6 34240714 34240736 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE94519 Sample Source: Blood Source Fraction: Serum Platform: GPL20115 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1224 Sample treatment protocol: All blood samples were separately collected and sequentially centrifuged at 2000 rpm for 10 min. The cell-free serum from the supernatant was stored at -80°C for further detection. RNA Extract protocol: RNA was prepared using the Versagene Blood RNA Purification kit (Gentra Systems, Minneapolis MN). RNA library preparation protocol: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the One-Color Low RNA Input Linear Amplification PLUS kit (Agilent) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA