exRNAdisease

General Information

Database ID:

exR0357002

RNA Name:

hsa-miR-382-5p

RNA Type:

miRNA

Chromosome:

chr14

Starnd:

Coordinate:

Start Site(bp):

101054316

End Site(bp):

101054337

External Links:

Disease Information

Disease Name:	Breast Cancer
Disease Category:	Cancers
MeSH ID:	D001943
Type:	Neoplasms/Breast Neoplasms
Alias:	Breast Neoplasms//Breast Neoplasm//Neoplasm, Breast//Breast Tumors//Breast Tumor//Tumor, Breast//Tumors, Breast//Neoplasms, Breast//Breast Cancer//Cancer, Breast//Mammary Cancer//Cancer, Mammary//Cancers, Mammary//Mammary Cancers//Malignant Neoplasm of Breast//Breast Malignant Neoplasm//Breast Malignant Neoplasms//Malignant Tumor of Breast//Breast Malignant Tumor//Breast Malignant Tumors//Cancer of Breast//Cancer of the Breast//Mammary Carcinoma, Human//Carcinoma, Human Mammary//Carcinomas, Human Mammary//Human Mammary Carcinomas//Mammary Carcinomas, Human//Human Mammary Carcinoma//Mammary Neoplasms, Human//Human Mammary Neoplasm//Human Mammary Neoplasms//Neoplasm, Human Mammary//Neoplasms, Human Mammary//Mammary Neoplasm, Human//Breast Carcinoma//Breast Carcinomas//Carcinoma, Breast//Carcinomas, Breast

Expression Detail

GEO ID:	GSE98181
Description:	Circulating miRNA profiles from serum of women at high-risk for breast cancer
Experimental Design:	Cancer vs Control
Case Disease Type:	Breast Cancer
Case Disease SubType:	NA
Case Sample:	Breast Cancer
Control Sample:	Healthy
Number of Case:	24
Number of Control:	24
Number of Samples:	48

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
APCDD1	chr18	10454635	10489949	+
BCAS2	chr1	114567557	114581629	-
BCL2L11	chr2	111119378	111168445	+
CAMTA1	chr1	6785454	7769706	+
COBLL1	chr2	164653624	164843679	-
ELK1	chrX	47635521	47650604	-
FOSL1	chr11	65892049	65900573	-
IGF2BP3	chr7	23310209	23470491	-
KMT5A	chr12	123383773	123409353	+
MAPRE2	chr18	34976928	35143470	+
NID1	chr1	235975830	236065109	-
PARM1	chr4	74933095	75050115	+
PDE8A	chr15	84980440	85139145	+
RAB18	chr10	27504174	27542237	+
SCAF11	chr12	45919131	45992120	-
SH3GL1	chr19	4360370	4400547	-
STEAP3	chr2	119223831	119265652	+
STK40	chr1	36339624	36385896	-
TAGLN	chr11	117199370	117207464	+
TUB	chr11	8019244	8106112	+
UBN2	chr7	139230356	139308236	+
WDR4	chr21	42843094	42879568	-

miRNA targets:

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC092718.4	chr16	81030770	81031485	+
AC126365.1	chr17	20788071	20789584	+
FGD5-AS1	chr3	14920347	14948424	-
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
TUG1	chr22	30969245	30979395	+

Display:

Experiment Detail

GEO ID:	GSE98181
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21572
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2546
Sample treatment protocol:	Serum is obtained from coagulated whole blood samples by centrifugation at 3000 rpm for 10 minutes.
RNA Extract protocol:	RNA was isolated from a 200ul serum aliquot using the miRNeasy Serum Plasma kit with ce-miR-39 spike-in (QIAGEN), QIAcube (QIAGEN) automation, and eluted with 14uL of nuclease-free water.
RNA library preparation protocol:	Exactly 8ul of RNA was tagged with a Poly-A tail, using an ATP driven reaction from the Affymetrix® FlashTag™ Biotin HSR RNA Labeling Kit.

Reference

PMID:	29348816
Title:	Development of a predictive miRNA signature for breast cancer risk among high-risk women.
Author:	Farina NH, Ramsey JE, Cuke ME, Ahern TP, Shirley DJ, Stein JL, Stein GS, Lian JB, Wood ME
Journal:	Oncotarget. 2017 Nov 28;8(68):112170-112183.
Description:	We evaluated the ability of C-miRNAs to identify women most likely to develop breast cancer by profiling miRNA from serum obtained long before diagnosis.