Entry Detail



General Information

Database ID:exR0358167
RNA Name:hsa-miR-671-5p
RNA Type:miRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):151238449End Site(bp):151238471
External Links:hsa-miR-671-5p



Disease Information

Disease Name:Breast Cancer
Disease Category:Cancers
MeSH ID:D001943
Type:Neoplasms/Breast Neoplasms
Alias:Breast Neoplasms//Breast Neoplasm//Neoplasm, Breast//Breast Tumors//Breast Tumor//Tumor, Breast//Tumors, Breast//Neoplasms, Breast//Breast Cancer//Cancer, Breast//Mammary Cancer//Cancer, Mammary//Cancers, Mammary//Mammary Cancers//Malignant Neoplasm of Breast//Breast Malignant Neoplasm//Breast Malignant Neoplasms//Malignant Tumor of Breast//Breast Malignant Tumor//Breast Malignant Tumors//Cancer of Breast//Cancer of the Breast//Mammary Carcinoma, Human//Carcinoma, Human Mammary//Carcinomas, Human Mammary//Human Mammary Carcinomas//Mammary Carcinomas, Human//Human Mammary Carcinoma//Mammary Neoplasms, Human//Human Mammary Neoplasm//Human Mammary Neoplasms//Neoplasm, Human Mammary//Neoplasms, Human Mammary//Mammary Neoplasm, Human//Breast Carcinoma//Breast Carcinomas//Carcinoma, Breast//Carcinomas, Breast



Expression Detail

GEO ID:GSE98181
Description:Circulating miRNA profiles from serum of women at high-risk for breast cancer
Experimental Design:Cancer vs Control
Case Disease Type:Breast Cancer
Case Disease SubType:NA
Case Sample:Breast Cancer
Control Sample:Healthy
Number of Case:24
Number of Control:24
Number of Samples:48





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RCOR1
chr14
102592649
102730561
+
KIAA0232
chr4
6781375
6884170
+
TAF8
chr6
42050513
42087461
+
MAFG
chr17
81918270
81927735
-
DYRK1A
chr21
37365573
37526358
+
MED22
chr9
133338312
133348131
-
KLC1
chr14
103561896
103714249
+
CBX6
chr22
38861422
38872249
-
SAMD4B
chr19
39342396
39385710
+
GTSE1
chr22
46296870
46330810
+
SETD5
chr3
9397615
9479240
+
CREG1
chr1
167529117
167553805
-
IRS2
chr13
109752695
109786583
-
SCAMP3
chr1
155255979
155262430
-
CCDC6
chr10
59788747
59906556
-
BAZ2A
chr12
56595596
56636816
-
WDR82
chr3
52254434
52288020
-
TOMM6
chr6
41787662
41789898
+
FAM219A
chr9
34398184
34458570
-
STAT3
chr17
42313324
42388568
-
UHRF1BP1
chr6
34792015
34883138
+
AL365205.1
chr6
41780349
41790141
+
NACC1
chr19
13116862
13141147
+
SMAD3
chr15
67063763
67195169
+
WDTC1
chr1
27234632
27308636
+
IL1R1
chr2
102064544
102179874
+
PTPRU
chr1
29236516
29326813
+
GLYR1
chr16
4803203
4847288
-
APLP2
chr11
130068147
130144811
+
CHTF8
chr16
69118010
69132578
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC067930.1
chr8
143579636
143580670
+
AC145207.5
chr17
81878425
81881106
-
AL022311.1
chr22
37876148
37895563
+
AL137127.1
chr1
19072110
19075511
-
H19
chr11
1995176
2001470
-
KCNQ1OT1
chr11
2608328
2699994
-
LINC01278
chrX
63222993
63561095
-
MIR29B2CHG
chr1
207801518
207879115
-
NEAT1
chr11
65422774
65445540
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE98181
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21572
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2546
Sample treatment protocol:Serum is obtained from coagulated whole blood samples by centrifugation at 3000 rpm for 10 minutes.
RNA Extract protocol:RNA was isolated from a 200ul serum aliquot using the miRNeasy Serum Plasma kit with ce-miR-39 spike-in (QIAGEN), QIAcube (QIAGEN) automation, and eluted with 14uL of nuclease-free water.
RNA library preparation protocol:Exactly 8ul of RNA was tagged with a Poly-A tail, using an ATP driven reaction from the Affymetrix® FlashTag™ Biotin HSR RNA Labeling Kit.



Reference

PMID:29348816
Title:Development of a predictive miRNA signature for breast cancer risk among high-risk women.
Author:Farina NH, Ramsey JE, Cuke ME, Ahern TP, Shirley DJ, Stein JL, Stein GS, Lian JB, Wood ME
Journal:Oncotarget. 2017 Nov 28;8(68):112170-112183.
Description:We evaluated the ability of C-miRNAs to identify women most likely to develop breast cancer by profiling miRNA from serum obtained long before diagnosis.