Entry Detail



General Information

Database ID:exR0358414
RNA Name:hsa-miR-6838-5p
RNA Type:miRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):44073407End Site(bp):44073428
External Links:hsa-miR-6838-5p



Disease Information

Disease Name:Breast Cancer
Disease Category:Cancers
MeSH ID:D001943
Type:Neoplasms/Breast Neoplasms
Alias:Breast Neoplasms//Breast Neoplasm//Neoplasm, Breast//Breast Tumors//Breast Tumor//Tumor, Breast//Tumors, Breast//Neoplasms, Breast//Breast Cancer//Cancer, Breast//Mammary Cancer//Cancer, Mammary//Cancers, Mammary//Mammary Cancers//Malignant Neoplasm of Breast//Breast Malignant Neoplasm//Breast Malignant Neoplasms//Malignant Tumor of Breast//Breast Malignant Tumor//Breast Malignant Tumors//Cancer of Breast//Cancer of the Breast//Mammary Carcinoma, Human//Carcinoma, Human Mammary//Carcinomas, Human Mammary//Human Mammary Carcinomas//Mammary Carcinomas, Human//Human Mammary Carcinoma//Mammary Neoplasms, Human//Human Mammary Neoplasm//Human Mammary Neoplasms//Neoplasm, Human Mammary//Neoplasms, Human Mammary//Mammary Neoplasm, Human//Breast Carcinoma//Breast Carcinomas//Carcinoma, Breast//Carcinomas, Breast



Expression Detail

GEO ID:GSE98181
Description:Circulating miRNA profiles from serum of women at high-risk for breast cancer
Experimental Design:Cancer vs Control
Case Disease Type:Breast Cancer
Case Disease SubType:NA
Case Sample:Breast Cancer
Control Sample:Healthy
Number of Case:24
Number of Control:24
Number of Samples:48





Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000540
chr14
55799534
55821940
+
hsa_circ_0001005
chr2
53921020
53978078
-
hsa_circ_0001723
chr7
91924202
91948826
+
hsa_circ_0000458
chr12
124071293
124074996
+
hsa_circ_0001699
chr7
40027197
40041630
+
hsa_circ_0001387
chr4
1902352
1936989
+
hsa_circ_0001168
chr20
47691321
47707559
+
hsa_circ_0000552
chr14
71880664
71948928
+
hsa_circ_0000038
chr1
28800065
28802803
+
hsa_circ_0000652
chr15
90984737
90986710
+
hsa_circ_0001472
chr5
36953719
36976504
+
hsa_circ_0001263
chr3
5215701
5216099
+
hsa_circ_0000799
chr17
65941524
65972074
+
hsa_circ_0001164
chr20
45891031
45923523
-
hsa_circ_0000032
chr1
25666964
25669564
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC003092.1
chr7
94022833
94066661
+
NUTM2B-AS1
chr10
79661394
79826594
-
LINC02035
chr3
122886941
122892416
+
AL031282.2
chr1
1702736
1737688
-
AC009022.1
chr16
69976297
70065948
-
AC020978.7
chr16
68224713
68227734
+
MIR29B2CHG
chr1
207801518
207879115
-
AC002470.2
chr22
20979462
20998121
+
LINC01184
chr5
127939152
128083172
-
SNHG12
chr1
28578538
28583132
-
XIST
chrX
73820649
73852723
-
AC021078.1
chr5
149494314
149504670
-
AC021092.1
chr19
44103007
44113183
-
AL359924.1
chr1
237862175
237928321
+
MIR497HG
chr17
7015818
7019659
-
HCG18
chr6
30286690
30327382
-
LINC00649
chr21
33915534
33977691
+
SNHG25
chr17
64145970
64146476
+
AC079781.5
chr7
97851688
97972985
-
AP000317.2
chr21
34073592
34360033
+
AC114980.1
chr5
93860669
93863825
-
NEAT1
chr11
65422774
65445540
+
SNHG16
chr17
76557764
76565348
+
LINC00662
chr19
27681072
27794005
-
MIR503HG
chrX
134543119
134546642
-
STAG3L5P-PVRIG2P-PILRB
chr7
100336104
100367831
+
AL391244.1
chr1
1420245
1422691
+
SNHG1
chr11
62851984
62855953
-
MCM3AP-AS1
chr21
46229196
46259390
+
MZF1-AS1
chr19
58559129
58574797
+
Display:



Experiment Detail

GEO ID:GSE98181
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21572
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2546
Sample treatment protocol:Serum is obtained from coagulated whole blood samples by centrifugation at 3000 rpm for 10 minutes.
RNA Extract protocol:RNA was isolated from a 200ul serum aliquot using the miRNeasy Serum Plasma kit with ce-miR-39 spike-in (QIAGEN), QIAcube (QIAGEN) automation, and eluted with 14uL of nuclease-free water.
RNA library preparation protocol:Exactly 8ul of RNA was tagged with a Poly-A tail, using an ATP driven reaction from the Affymetrix® FlashTag™ Biotin HSR RNA Labeling Kit.



Reference

PMID:29348816
Title:Development of a predictive miRNA signature for breast cancer risk among high-risk women.
Author:Farina NH, Ramsey JE, Cuke ME, Ahern TP, Shirley DJ, Stein JL, Stein GS, Lian JB, Wood ME
Journal:Oncotarget. 2017 Nov 28;8(68):112170-112183.
Description:We evaluated the ability of C-miRNAs to identify women most likely to develop breast cancer by profiling miRNA from serum obtained long before diagnosis.