exRNAdisease

Entry Detail

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General Information

Database ID: exR0410024 RNA Name: DANCR RNA Type: lncRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 52712404 End Site(bp): 52720351 External Links: ENSG00000226950

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF1 chr6 30571393 30597179 + ABHD14A-ACY1 chr3 51974706 51989183 + AC009690.1 chr15 72284727 72375981 - ACOT7 chr1 6264269 6394391 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACVR1B chr12 51951699 51997078 + ACY1 chr3 51983340 51989197 + AKT2 chr19 40230317 40285536 - AL358113.1 chr9 69035747 69255187 + ALDOA chr16 30064164 30070457 + AC139530.2 chr17 81703371 81720539 + AKIP1 chr11 8911139 8920084 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-33a-5p chr22 41900949 41900969 + hsa-miR-216a-5p chr2 55989020 55989041 - hsa-miR-125b-5p chr21 16590253 16590274 + hsa-miR-135a-5p chr12 97563834 97563856 + hsa-miR-125a-5p chr19 51693268 51693291 + hsa-miR-135b-5p chr1 205448361 205448383 - hsa-miR-496 chr14 101060628 101060649 + hsa-miR-33b-5p chr17 17813897 17813916 - hsa-miR-656-3p chr14 101066766 101066786 + hsa-miR-758-3p chr14 101026071 101026092 + hsa-miR-214-5p chr1 172138857 172138878 - hsa-miR-874-3p chr5 137647582 137647603 - hsa-miR-1301-3p chr2 25328651 25328674 - hsa-miR-3180-3p chr16 16309936 16309957 + hsa-miR-3196 chr20 63238788 63238805 + hsa-miR-3200-3p chr22 30731610 30731631 + hsa-miR-4319 chr18 44970140 44970156 - hsa-miR-3180 chr16 15154949 15154967 - hsa-miR-4436a chr2 88812425 88812445 + hsa-miR-1343-3p chr11 34941888 34941909 + hsa-miR-5047 chr17 64501230 64501250 - hsa-miR-5000-3p chr2 75090873 75090894 + hsa-miR-506-5p chrX 147230788 147230809 - hsa-miR-1277-5p chrX 118386401 118386424 + hsa-miR-1306-5p chr22 20086072 20086093 + hsa-miR-6783-3p chr17 44934618 44934639 - hsa-miR-6816-5p chr22 20114726 20114746 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA