exRNAdisease

General Information

Database ID:

exR0410033

RNA Name:

DHRS4-AS1

RNA Type:

lncRNA

Chromosome:

chr14

Starnd:

Coordinate:

Start Site(bp):

23938219

End Site(bp):

24052555

External Links:

Disease Information

Disease Name:	Clear Cell Renal Cell Carcinoma
Disease Category:	Cancers
MeSH ID:	D002292
Type:	Neoplasms/Urogenital Neoplasms
Alias:	Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID:	GSE125442
Description:	Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma
Experimental Design:	Cancer vs Control
Case Disease Type:	Clear Cell Renal Cell Carcinoma
Case Disease SubType:	NA
Case Sample:	Clear Cell Renal Cell Carcinoma
Control Sample:	Healthy
Number of Case:	10
Number of Control:	10
Number of Samples:	20

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AHCY	chr20	34280268	34311802	-

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-140-5p	chr16	69933103	69933124	+
hsa-miR-143-3p	chr5	149428978	149428998	+
hsa-miR-522-3p	chr19	53751264	53751285	+
hsa-miR-584-5p	chr5	149062373	149062394	-
hsa-miR-660-5p	chrX	50013256	50013277	+
hsa-miR-545-5p	chrX	74287164	74287185	-
hsa-miR-624-3p	chr14	31014669	31014689	-
hsa-miR-513b-5p	chrX	147199093	147199114	-
hsa-miR-224-3p	chrX	151958584	151958606	-
hsa-miR-2681-3p	chr13	101967665	101967686	-
hsa-miR-6088	chr19	45436654	45436673	+

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC084082.1	chr8	66112667	66126632	+

Display:

Experiment Detail

GEO ID:	GSE125442
Sample Source:	Urine
Source Fraction:	Exosome
Platform:	GPL21290
Method:	NGS
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	882
Sample treatment protocol:	Exosomes were isolated by ultracentrifugation from 50-ml urine samples.
RNA Extract protocol:	A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol.
RNA library preparation protocol:	Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference