exRNAdisease

Entry Detail

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General Information

Database ID: exR0410137 RNA Name: GAS5 RNA Type: lncRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 173858559 End Site(bp): 173868882 External Links: ENSG00000234741

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC1 chr16 15949577 16143074 + AC104109.3 chr5 134167170 134226071 - ACSS2 chr20 34872146 34927962 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + AGFG1 chr2 227472152 227561214 + AL133352.1 chr10 100505628 100529881 - AC013394.1 chr15 92883413 92949230 + AC026954.2 chr17 7312661 7319174 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4766-5p chr22 40813927 40813947 - hsa-miR-361-5p chrX 85903681 85903702 - hsa-miR-4640-3p chr6 30890949 30890970 + hsa-miR-4676-3p chr10 72721072 72721093 + hsa-miR-320b chr1 224257049 224257070 - hsa-miR-532-5p chrX 50003167 50003188 + hsa-miR-515-5p chr19 53685022 53685045 + hsa-miR-346 chr10 86264747 86264769 - hsa-miR-5579-3p chr11 79422169 79422190 - hsa-miR-6807-3p chr19 58550354 58550376 + hsa-miR-374b-5p chrX 74218587 74218608 - hsa-miR-196a-5p chr17 48632532 48632553 - hsa-miR-579-3p chr5 32394392 32394414 - hsa-miR-374a-5p chrX 74287325 74287346 - hsa-miR-320a-3p chr8 22244975 22244996 - hsa-miR-3127-5p chr2 96798288 96798310 + hsa-miR-345-5p chr14 100307876 100307897 + hsa-miR-223-3p chrX 66018937 66018958 + hsa-miR-525-5p chr19 53697547 53697567 + hsa-miR-524-5p chr19 53711017 53711038 + hsa-miR-548o-3p chr20 38516607 38516628 + hsa-miR-744-5p chr17 12081909 12081930 + hsa-miR-144-5p chr17 28861583 28861604 - hsa-miR-1908-5p chr11 61815209 61815229 - hsa-miR-23a-3p chr19 13836595 13836615 - hsa-miR-509-3p chrX 147258775 147258796 - hsa-miR-320d chr13 40727828 40727846 - hsa-miR-3622b-5p chr8 27701726 27701745 - hsa-miR-1251-5p chr12 97491913 97491933 + hsa-miR-892c-3p chrX 145992760 145992781 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC009446.1 chr8 71675300 71702786 + AC016876.2 chr17 7581964 7584086 - AC027644.3 chr7 66739829 66740385 - AC055860.1 chr11 18000542 18022931 - AC138207.2 chr17 31090787 31095450 - AL117378.1 chr6 131901963 131920565 + Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA