exRNAdisease

Entry Detail

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General Information

Database ID: exR0410160 RNA Name: HCG18 RNA Type: lncRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 30286690 End Site(bp): 30327382 External Links: ENSG00000231074

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKT1S1 chr19 49869033 49878459 - AKT2 chr19 40230317 40285536 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-545-5p chrX 74287164 74287185 - hsa-miR-324-5p chr17 7223343 7223364 - hsa-miR-4677-3p chr1 243346225 243346246 + hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-148b-3p chr12 54337278 54337299 + hsa-miR-4739 chr17 79707216 79707240 - hsa-miR-3174 chr15 90006764 90006786 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-148a-3p chr7 25949922 25949943 - hsa-miR-449c-5p chr5 55172313 55172337 - hsa-miR-449a chr5 55170586 55170607 - hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-4756-5p chr20 54068452 54068474 - hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-499a-5p chr20 34990408 34990428 + hsa-miR-3614-5p chr17 56891319 56891341 - hsa-miR-495-3p chr14 101033804 101033825 + hsa-miR-3605-5p chr1 33332449 33332471 - hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-5688 chr3 85385761 85385782 + hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-6838-5p chr7 44073407 44073428 - hsa-miR-4508 chr15 23562107 23562123 - hsa-miR-34b-5p chr11 111512950 111512972 + hsa-miR-2682-5p chr1 98045307 98045329 - hsa-miR-499b-5p chr20 34990443 34990463 - hsa-miR-34c-5p chr11 111513451 111513473 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL022157.1 chrX 57121662 57127243 + Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA