exRNAdisease

General Information

Database ID:

exR0410173

RNA Name:

HOTAIR

RNA Type:

lncRNA

Chromosome:

chr12

Starnd:

Coordinate:

Start Site(bp):

53962308

End Site(bp):

53974956

External Links:

Disease Information

Disease Name:	Clear Cell Renal Cell Carcinoma
Disease Category:	Cancers
MeSH ID:	D002292
Type:	Neoplasms/Urogenital Neoplasms
Alias:	Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID:	GSE125442
Description:	Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma
Experimental Design:	Cancer vs Control
Case Disease Type:	Clear Cell Renal Cell Carcinoma
Case Disease SubType:	NA
Case Sample:	Clear Cell Renal Cell Carcinoma
Control Sample:	Healthy
Number of Case:	10
Number of Control:	10
Number of Samples:	20

Regulatory Relationship

mRNA targets:

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-17-5p	chr13	91350618	91350640	+
hsa-miR-20a-5p	chr13	91351072	91351094	+
hsa-miR-93-5p	chr7	100093815	100093837	-
hsa-miR-106a-5p	chrX	134170244	134170266	-
hsa-miR-126-5p	chr9	136670616	136670636	+
hsa-miR-106b-5p	chr7	100094043	100094063	-
hsa-miR-20b-5p	chrX	134169850	134169872	-
hsa-miR-519c-3p	chr19	53686522	53686543	+
hsa-miR-526b-3p	chr19	53694443	53694464	+
hsa-miR-519b-3p	chr19	53695263	53695284	+
hsa-miR-519d-3p	chr19	53713400	53713421	+
hsa-miR-520g-3p	chr19	53722220	53722243	+
hsa-miR-520h	chr19	53742566	53742587	+
hsa-miR-519a-3p	chr19	53762397	53762418	+
hsa-miR-1277-5p	chrX	118386401	118386424	+

circRNA targets:

lncRNA targets:

Display:

Experiment Detail

GEO ID:	GSE125442
Sample Source:	Urine
Source Fraction:	Exosome
Platform:	GPL21290
Method:	NGS
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	882
Sample treatment protocol:	Exosomes were isolated by ultracentrifugation from 50-ml urine samples.
RNA Extract protocol:	A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol.
RNA library preparation protocol:	Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference