exRNAdisease

Entry Detail

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General Information

Database ID: exR0410209 RNA Name: KCNQ1OT1 RNA Type: lncRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 2608328 End Site(bp): 2699994 External Links: ENSG00000269821

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADAT1 chr16 75596981 75623300 - AL355315.1 chr10 97584374 97673910 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4640-5p chr6 30890891 30890913 + hsa-miR-196b-5p chr7 27169528 27169549 - hsa-miR-378d chr4 5923279 5923298 - hsa-miR-129-2-3p chr11 43581450 43581471 + hsa-miR-98-5p chrX 53556299 53556320 - hsa-miR-4644 chr6 170330813 170330835 + hsa-let-7g-5p chr3 52268336 52268357 - hsa-miR-140-3p chr16 69933142 69933162 + hsa-miR-324-3p chr17 7223308 7223330 - hsa-miR-3918 chr6 158764715 158764735 - hsa-miR-1914-3p chr20 63941474 63941495 - hsa-miR-378c chr10 130962634 130962658 - hsa-let-7b-5p chr22 46113691 46113712 + hsa-miR-339-3p chr7 1022955 1022977 - hsa-miR-181a-5p chr1 198859108 198859130 - hsa-miR-214-5p chr1 172138857 172138878 - hsa-miR-605-3p chr10 51299623 51299644 + hsa-miR-513b-5p chrX 147199093 147199114 - hsa-miR-5581-3p chr1 37500935 37500956 - hsa-miR-124-3p chr8 64379210 64379231 + hsa-miR-2278 chr9 94809977 94809998 + hsa-miR-532-3p chrX 50003204 50003225 + hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-145-5p chr5 149430661 149430683 + hsa-miR-4756-5p chr20 54068452 54068474 - hsa-miR-362-3p chrX 50009005 50009026 + hsa-miR-134-5p chr14 101054694 101054715 + hsa-miR-148a-3p chr7 25949922 25949943 - hsa-let-7i-5p chr12 62603691 62603712 + hsa-miR-4524b-5p chr17 69099570 69099590 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005034.3 chr2 75697583 75697996 + AC010186.4 chr12 9642872 9657070 + AC026471.1 chr16 31456711 31459736 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA