exRNAdisease

General Information

Database ID:

exR0410405

RNA Name:

LINC00662

RNA Type:

lncRNA

Chromosome:

chr19

Starnd:

Coordinate:

Start Site(bp):

27681072

End Site(bp):

27794005

External Links:

Disease Information

Disease Name:	Clear Cell Renal Cell Carcinoma
Disease Category:	Cancers
MeSH ID:	D002292
Type:	Neoplasms/Urogenital Neoplasms
Alias:	Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID:	GSE125442
Description:	Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma
Experimental Design:	Cancer vs Control
Case Disease Type:	Clear Cell Renal Cell Carcinoma
Case Disease SubType:	NA
Case Sample:	Clear Cell Renal Cell Carcinoma
Control Sample:	Healthy
Number of Case:	10
Number of Control:	10
Number of Samples:	20

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ACTB	chr7	5527148	5563784	-
AC005837.2	chr17	76732978	76738522	+

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-15a-5p	chr13	50049167	50049188	-
hsa-miR-16-5p	chr3	160404754	160404775	+
hsa-miR-103a-3p	chr5	168560904	168560926	-
hsa-miR-107	chr10	89592756	89592778	-
hsa-miR-15b-5p	chr3	160404607	160404628	+
hsa-miR-144-3p	chr17	28861548	28861567	-
hsa-miR-195-5p	chr17	7017667	7017687	-
hsa-miR-424-5p	chrX	134546680	134546701	-
hsa-miR-497-5p	chr17	7017979	7017999	-
hsa-miR-340-5p	chr5	180015361	180015382	-
hsa-miR-1323	chr19	53671978	53671999	+
hsa-miR-548o-3p	chr20	38516607	38516628	+
hsa-miR-3163	chr11	66934476	66934497	-
hsa-miR-4524a-5p	chr17	69099606	69099627	-
hsa-miR-4524b-5p	chr17	69099570	69099590	+
hsa-miR-6838-5p	chr7	44073407	44073428	-

circRNA targets:

lncRNA targets:

Display:

Experiment Detail

GEO ID:	GSE125442
Sample Source:	Urine
Source Fraction:	Exosome
Platform:	GPL21290
Method:	NGS
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	882
Sample treatment protocol:	Exosomes were isolated by ultracentrifugation from 50-ml urine samples.
RNA Extract protocol:	A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol.
RNA library preparation protocol:	Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference