exRNAdisease

General Information

Database ID:

exR0410465

RNA Name:

MCM3AP-AS1

RNA Type:

lncRNA

Chromosome:

chr21

Starnd:

Coordinate:

Start Site(bp):

46229196

End Site(bp):

46259390

External Links:

Disease Information

Disease Name:	Clear Cell Renal Cell Carcinoma
Disease Category:	Cancers
MeSH ID:	D002292
Type:	Neoplasms/Urogenital Neoplasms
Alias:	Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID:	GSE125442
Description:	Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma
Experimental Design:	Cancer vs Control
Case Disease Type:	Clear Cell Renal Cell Carcinoma
Case Disease SubType:	NA
Case Sample:	Clear Cell Renal Cell Carcinoma
Control Sample:	Healthy
Number of Case:	10
Number of Control:	10
Number of Samples:	20

Regulatory Relationship

mRNA targets:

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-520d-5p	chr19	53720111	53720130	+
hsa-miR-6849-5p	chr8	144400318	144400340	-
hsa-miR-642b-3p	chr19	45674941	45674962	-
hsa-miR-138-5p	chr16	56858527	56858549	+
hsa-miR-497-5p	chr17	7017979	7017999	-
hsa-miR-204-5p	chr9	70810031	70810052	-
hsa-miR-642a-3p	chr19	45674978	45674999	+
hsa-miR-1323	chr19	53671978	53671999	+
hsa-miR-19b-3p	chr13	91351245	91351267	+
hsa-miR-6783-3p	chr17	44934618	44934639	-
hsa-miR-15a-5p	chr13	50049167	50049188	-
hsa-miR-4524a-5p	chr17	69099606	69099627	-
hsa-miR-425-5p	chr3	49020199	49020221	-
hsa-miR-194-5p	chr11	64891404	64891425	-
hsa-miR-548o-3p	chr20	38516607	38516628	+
hsa-miR-5581-3p	chr1	37500935	37500956	-
hsa-miR-374c-3p	chrX	74218587	74218608	+
hsa-miR-195-5p	chr17	7017667	7017687	-
hsa-miR-15b-5p	chr3	160404607	160404628	+
hsa-miR-5586-5p	chr14	59646999	59647020	-
hsa-miR-130a-5p	chr11	57641212	57641233	+
hsa-miR-383-5p	chr8	14853483	14853504	-
hsa-miR-4524b-5p	chr17	69099570	69099590	+
hsa-miR-1343-3p	chr11	34941888	34941909	+
hsa-miR-6838-5p	chr7	44073407	44073428	-
hsa-miR-524-5p	chr19	53711017	53711038	+
hsa-miR-380-3p	chr14	101025056	101025077	+
hsa-miR-211-5p	chr15	31065095	31065116	-
hsa-miR-23a-3p	chr19	13836595	13836615	-
hsa-miR-205-5p	chr1	209432166	209432187	+

circRNA targets:

lncRNA targets:

Display:

Experiment Detail

GEO ID:	GSE125442
Sample Source:	Urine
Source Fraction:	Exosome
Platform:	GPL21290
Method:	NGS
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	882
Sample treatment protocol:	Exosomes were isolated by ultracentrifugation from 50-ml urine samples.
RNA Extract protocol:	A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol.
RNA library preparation protocol:	Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference