exRNAdisease

Entry Detail

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General Information

Database ID: exR0410478 RNA Name: MIR17HG RNA Type: lncRNA Chromosome: chr13 Starnd: + Coordinate: Start Site(bp): 91347820 End Site(bp): 91354579 External Links: ENSG00000215417

Disease Information

Disease Name: Clear Cell Renal Cell Carcinoma Disease Category: Cancers MeSH ID: D002292 Type: Neoplasms/Urogenital Neoplasms Alias: Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID: GSE125442 Description: Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma Experimental Design: Cancer vs Control Case Disease Type: Clear Cell Renal Cell Carcinoma Case Disease SubType: NA Case Sample: Clear Cell Renal Cell Carcinoma Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC131160.1 chr3 183815568 183884889 - ACSS2 chr20 34872146 34927962 + ADNP chr20 50888916 50931437 - ACOT13 chr6 24667035 24705065 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3619-5p chr22 46091059 46091080 + hsa-miR-302a-3p chr4 112648186 112648208 - hsa-miR-5000-3p chr2 75090873 75090894 + hsa-miR-301a-3p chr17 59151149 59151171 - hsa-miR-194-5p chr11 64891404 64891425 - hsa-miR-520a-3p chr19 53690933 53690954 + hsa-miR-624-3p chr14 31014669 31014689 - hsa-miR-3666 chr7 114653373 114653393 + hsa-miR-377-3p chr14 101062094 101062115 + hsa-miR-4295 chr10 112634180 112634197 + hsa-miR-519c-3p chr19 53686522 53686543 + hsa-miR-520c-3p chr19 53707506 53707527 + hsa-miR-579-3p chr5 32394392 32394414 - hsa-miR-761 chr1 51836375 51836396 - hsa-miR-302e chr11 7234771 7234787 + hsa-miR-1323 chr19 53671978 53671999 + hsa-miR-502-3p chrX 50014649 50014670 + hsa-miR-1252-5p chr12 79419261 79419282 + hsa-miR-3173-5p chr14 95137961 95137982 - hsa-miR-520d-3p chr19 53720149 53720170 + hsa-miR-548o-3p chr20 38516607 38516628 + hsa-miR-28-3p chr3 188688834 188688855 + hsa-miR-500a-3p chrX 50008482 50008503 + hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-153-3p chr2 219294126 219294147 - hsa-miR-92a-1-5p chr13 91351324 91351346 + hsa-miR-4436a chr2 88812425 88812445 + hsa-miR-664b-3p chrX 154768635 154768656 + hsa-miR-6799-3p chr19 49791912 49791934 + hsa-miR-454-3p chr17 59137787 59137809 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE125442 Sample Source: Urine Source Fraction: Exosome Platform: GPL21290 Method: NGS Num of detected RNA Type: 1 Num of detected RNAs of this Type: 882 Sample treatment protocol: Exosomes were isolated by ultracentrifugation from 50-ml urine samples. RNA Extract protocol: A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol. RNA library preparation protocol: Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA