exRNAdisease

General Information

Database ID:

exR0410485

RNA Name:

MIR497HG

RNA Type:

lncRNA

Chromosome:

chr17

Starnd:

Coordinate:

Start Site(bp):

7015818

End Site(bp):

7019659

External Links:

Disease Information

Disease Name:	Clear Cell Renal Cell Carcinoma
Disease Category:	Cancers
MeSH ID:	D002292
Type:	Neoplasms/Urogenital Neoplasms
Alias:	Carcinoma, Renal Cell//Carcinomas, Renal Cell//Renal Cell Carcinomas//Adenocarcinoma, Renal Cell//Adenocarcinomas, Renal Cell//Renal Cell Adenocarcinoma//Renal Cell Adenocarcinomas//Adenocarcinoma Of Kidney//Adenocarcinoma Of Kidneys//Kidney, Adenocarcinoma Of//Kidneys, Adenocarcinoma Of//Renal Cell Cancer//Cancer, Renal Cell//Cancers, Renal Cell//Renal Cell Cancers//Adenocarcinoma, Renal//Adenocarcinomas, Renal//Renal Adenocarcinoma//Renal Adenocarcinomas//Nephroid Carcinoma//Carcinoma, Nephroid//Carcinomas, Nephroid//Nephroid Carcinomas//Renal Cell Carcinoma//Chromophobe Renal Cell Carcinoma//Sarcomatoid Renal Cell Carcinoma//Papillary Renal Cell Carcinoma//Renal Cell Carcinoma, Papillary//Chromophil Renal Cell Carcinoma//Clear Cell Renal Cell Carcinoma//Grawitz Tumor//Tumor, Grawitz//Clear Cell Renal Carcinoma//Carcinoma, Hypernephroid//Carcinomas, Hypernephroid//Hypernephroid Carcinoma//Hypernephroid Carcinomas//Hypernephroma//Hypernephromas//Collecting Duct Carcinoma (Kidney)//Carcinoma, Collecting Duct (Kidney)//Carcinomas, Collecting Duct (Kidney)//Collecting Duct Carcinomas (Kidney)//Collecting Duct Carcinoma of the Kidney//Renal Collecting Duct Carcinoma//Collecting Duct Carcinoma//Carcinoma, Collecting Duct//Carcinomas, Collecting Duct//Collecting Duct Carcinomas

Expression Detail

GEO ID:	GSE125442
Description:	Urinary exosomal long noncoding RNAs may be novel biomarkers for the diagnosis of clear cell renal cell carcinoma
Experimental Design:	Cancer vs Control
Case Disease Type:	Clear Cell Renal Cell Carcinoma
Case Disease SubType:	NA
Case Sample:	Clear Cell Renal Cell Carcinoma
Control Sample:	Healthy
Number of Case:	10
Number of Control:	10
Number of Samples:	20

Regulatory Relationship

mRNA targets:

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-195-5p	chr17	7017667	7017687	-
hsa-miR-3187-3p	chr19	813627	813646	+
hsa-miR-642a-5p	chr19	45674943	45674964	+
hsa-miR-4525	chr17	82668281	82668301	-
hsa-miR-1306-5p	chr22	20086072	20086093	+
hsa-miR-488-3p	chr1	177029374	177029394	-
hsa-miR-942-5p	chr1	117094655	117094676	+
hsa-miR-424-5p	chrX	134546680	134546701	-
hsa-miR-197-3p	chr1	109598940	109598961	+
hsa-miR-497-5p	chr17	7017979	7017999	-
hsa-miR-29c-3p	chr1	207801865	207801886	-
hsa-miR-128-3p	chr2	135665446	135665466	+
hsa-miR-371a-3p	chr19	53787716	53787738	+
hsa-miR-16-5p	chr3	160404754	160404775	+
hsa-miR-3180	chr16	15154949	15154967	-
hsa-miR-29a-3p	chr7	130876748	130876769	-
hsa-miR-588	chr6	126484646	126484666	+
hsa-miR-526b-5p	chr19	53694406	53694428	+
hsa-miR-512-3p	chr19	53666729	53666750	+
hsa-miR-513b-5p	chrX	147199093	147199114	-
hsa-miR-599	chr8	99536651	99536670	-
hsa-miR-3681-3p	chr2	12199174	12199195	+
hsa-miR-4701-5p	chr12	48772014	48772035	-
hsa-miR-140-3p	chr16	69933142	69933162	+
hsa-miR-3180-3p	chr16	16309936	16309957	+
hsa-miR-642b-5p	chr19	45674978	45674999	-
hsa-miR-665	chr14	100875075	100875094	+
hsa-miR-4731-5p	chr17	15251666	15251687	-
hsa-miR-3918	chr6	158764715	158764735	-
hsa-miR-1266-3p	chr15	52277131	52277152	-

circRNA targets:

lncRNA targets:

Display:

Experiment Detail

GEO ID:	GSE125442
Sample Source:	Urine
Source Fraction:	Exosome
Platform:	GPL21290
Method:	NGS
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	882
Sample treatment protocol:	Exosomes were isolated by ultracentrifugation from 50-ml urine samples.
RNA Extract protocol:	A MiRNeasy Serum/Plasma Kit (QIAGEN, Valencia, CA, USA) was used to extract RNA from urinary exosome samples in accordance with the manufacturer's protocol.
RNA library preparation protocol:	Fragmented RNA (the average length was approximately 200 bp) were subjected to first strand and second strand cDNA synthesis following by adaptor ligation and enrichment with a low-cycle according to instructions of NEBNext® Ultra™ RNA Library Prep Kit for Illumina (NEB, USA).

Reference